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|a Phillips, Kirk A.
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|a Total Exposure Health :
|b An Introduction.
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|a Milton :
|b Taylor & Francis Group,
|c 2020.
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|c ©2020.
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|a 1 online resource (353 pages)
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|a text
|b txt
|2 rdacontent
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|a computer
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|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a Environmental and Occupational Health Ser.
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|a Cover -- Half Title -- Series Page -- Title Page -- Copyright Page -- Dedication -- Table of Contents -- Foreword -- Preface -- Acknowledgments -- Editors -- Contributors -- Section I: Overview and Fundamentals -- Chapter 1 Total Exposure Health: An Exposure Science Framework for the Fourth Industrial Age -- 1.1 Origins of Total Exposure Health -- 1.1.2 The Steadfast Practice of Industrial Hygiene -- 1.1.3 Exposures and Exposed Populations Are Decreasing -- 1.1.4 Sensors Are (Almost) Ubiquitous -- 1.1.5 Expanded Knowledge of Disease, Mechanisms of Disease, and Genetics -- 1.2 Aims of Total Exposure Health -- 1.3 The Totals Explained -- 1.3.1 Total Worker Health[sup(®)] -- 1.3.2 Total Worker Exposure (TWE) -- 1.3.3 Total Exposure Health(TEH) -- 1.4 TEH Exposures of Concern -- 1.4.1 Occupational -- 1.4.2 Environment -- 1.4.3 Lifestyle -- 1.4.4 Clinical -- 1.5 TEH Exposure Data Sources -- 1.5.1 Workplace IH -- 1.5.2 Environmental and Community Health -- 1.5.3 Personal Environmental Exposure Sensors and the Internet of Things -- 1.6 Healthcare Is Changing-Personalized Healthcare -- 1.6.1 Patient Centric -- 1.6.2 Exposure Curves: Where Does an Individual Fit In -- 1.7 The Fourth Industrial Revolution and TEH -- 1.7.1 Computational Toxicology -- 1.7.2 Genetic Expression -- 1.8 Novel Controls Additions to the Hierarchy -- 1.8.1 Individual Exposure Health Risk Profile (IEHRP) -- 1.8.2 Preexposure Prophylaxis -- 1.8.3 Self-Limiting Exposures -- 1.8.4 Nonoccupational PPE/Increased Occupational PPE -- 1.8.5 Durable Medical Equipment -- 1.8.6 Blood Chemistry Tracking -- 1.9 TEH-Bringing It All Together -- References -- Chapter 2 The Individual Exposure Health Risk Profile (IEHRP)- Developing a Risk Profile Tool beyond Dose Response -- 2.1 Introduction -- 2.2 Total Exposure Health (TEH) -- 2.3 Noise Exposure Demonstration Project (NEDP).
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|a 2.4 Individual Exposure Health Risk Profile (IEHRP) -- 2.5 Conclusion -- References -- Chapter 3 In Pursuit of Total Exposure Health: Leveraging Exposure Science, the Omics, and Other Emerging Technologies -- 3.1 Introduction -- 3.2 Exposure Science: Key Principles Useful for Total Exposure Health -- 3.3 High-Throughput Metabolomics in Total Exposure Health -- 3.3.1 The Omics -- 3.3.2 Metabolomics -- 3.3.2.1 Targeted Metabolomics -- 3.3.2.2 Untargeted Metabolomics -- 3.3.3 Growth of Metabolomics -- 3.4 The Human Microbiome as a Modifier of Personalized Exposures -- 3.4.1 The Microbiome of a Baby -- 3.4.2 The Gut Microbiome -- 3.5 Pharmacokinetics -- 3.5.1 Absorption, Distribution, Metabolism, and Excretion -- 3.5.2 Physiologically Based Pharmacokinetic (PBPK) Modeling -- 3.6 Conclusions -- References -- Chapter 4 Total Worker Health : Bridging Worker Exposure and Well-Being -- 4.1 Introduction -- 4.2 What Is TWH? -- 4.2.1 Comparing the TWH Approach -- 4.2.2 Issues Relevant to Advancing Worker Well-Being through Total Worker Health[sup(®)] -- 4.2.3 What TWH Looks Like in Practice -- 4.3 The 1st and 2nd International Symposia to Advance Total Worker Health[sup(®)] -- 4.4 Advances in Research -- 4.4.1 National Total Worker Health[sup(®)] Agenda -- 4.4.2 Total Worker Health Research Methodology Workshop -- 4.4.3 Worker Well-Being Framework -- 4.4.4 Centers of Excellence for TWH -- 4.5 Research to Practice -- 4.5.1 Fundamentals of Total Worker Health[sup(®)] Approaches -- 4.5.2 Hierarchy of Controls Applied to NIOSH Total Worker Health[sup(®)] -- 4.6 Determining Overall Risk and Exposure for Worker Safety, Health, and Well-Being -- 4.6.1 Cumulative Risk Assessment -- 4.6.2 Total Exposure Health -- 4.6.3 TWH, CRA, and TEH -- 4.7 Partnership and Stakeholder Involvement -- 4.7.1 NIOSH TWH Affiliates -- 4.7.2 Collaborative Activities -- 4.8 Conclusion.
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|a References -- Chapter 5 Industrial Hygiene: A Foundational Role in Total Exposure Health -- 5.1 Introduction -- 5.2 What Is Industrial Hygiene? -- 5.2.1 Definition of Industrial Hygiene -- 5.2.2 OSHA Compliance -- 5.3 History of Industrial Hygiene -- 5.3.1 Early Names in IH -- 5.3.2 Academic Programs and ABET -- 5.3.3 Professional Organizations -- 5.3.3.1 American Conference of Governmental Industrial Hygienists (ACGIH[sup(®)]) -- 5.3.3.2 American Industrial Hygiene Association (AIHA[sup(®)]) -- 5.3.3.3 Board for Global EHS Credentialing (BGC[sup(®)]) -- 5.3.3.4 Occupational Safety and Health Administration (OSHA) -- 5.3.3.5 National Institute for Occupational Safety and Health (NIOSH) -- 5.4 Today's Industrial Hygiene -- 5.4.1 Anticipation-Recognition-Evaluation-Control-Confirm -- 5.4.1.1 Anticipation -- 5.4.1.2 Recognition -- 5.4.1.3 Evaluation -- 5.4.1.4 Control -- 5.4.1.5 Confirm -- 5.4.2 Exposure Assessment: A Core Function of Industrial Hygiene -- 5.4.2.1 Exposure Assessment-Defined -- 5.4.2.2 Comprehensive Exposure Assessment-More than Compliance -- 5.5 The Future of Industrial Hygiene and Total Exposure Health -- 5.5.1 Industrial Hygienists: Ready for Total Exposure Health -- 5.5.2 Challenges for Industrial Hygienists in Fulfilling TEH -- References -- Section II: Advances in Toxicology and the -Omics -- Chapter 6 Personalizing Environmental Health for the Military-Striving for Precision -- 6.1 The Need for Precision in Military Environmental Health -- 6.2 From Past to Present: The Changing Landscape of Precision Medicine -- 6.2.1 Technology and Medicine -- 6.2.2 Genetics versus Genomics -- 6.2.3 Genomics and the Overpromise of GWAS -- 6.2.4 Sequencing and 'Omics' Technology Advancements -- 6.2.5 The 'Great GWAS Do-over'? -- 6.2.6 Incorporating the Changing Landscape of Genomics into the Clinic over Time.
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|a 6.3 Precision beyond Genomics: Environment, Exposures, and Social Background -- 6.3.1 Getting More Personal: The Microbiome as an Interface -- 6.3.2 Models of Risk and Exposure -- 6.3.3 Likelihood Ratio (LR) -- 6.3.4 Social Determinants of Health (SDOH) -- 6.4 Precision Medicine and Environmental Health for the Military -- 6.4.1 The Million Veterans Program -- 6.4.2 Ethical, Legal, and Social Issues (ELSI) -- 6.5 Outlook -- References -- Chapter 7 In Silico Identification of Protein Targets for Chemical Neurotoxins Using ToxCast in Vitro Data and Read-Across within the QSAR Toolbox -- 7.1 Introduction -- 7.2 Materials and Methods -- 7.2.1 ToxCast Compound Dataset -- 7.2.2 Bioactivity Data Associated with Neurotoxicity -- 7.2.3 Performance Evaluation -- 7.2.4 Software -- 7.3 Results and Discussion -- 7.4 Conclusions -- 7.5 Conflict of Interest -- 7.6 Acknowledgments -- References -- Chapter 8 "Omics": An Introduction -- 8.1 Introduction -- 8.2 Genomics -- 8.2.1 Sequencing Technologies -- 8.2.2 Utility of Whole-Genome Sequence in Total Exposure Health -- 8.3 Transcriptomics -- 8.3.1 Analytic Methods for Transcriptomics -- 8.3.2 Transcriptomics Role in TEH -- 8.4 Epigenomics -- 8.4.1 Measuring Epigenomic Marks -- 8.4.2 The Epigenome in TEH -- 8.5 Proteome -- 8.5.1 Proteomics Methods -- 8.5.2 Proteomics Utility in TEH -- 8.6 Metabolome -- 8.6.1 Metabolome Methods -- 8.6.2 Metabolome in TEH -- 8.7 Microbiome -- 8.7.1 Enumerating the Microbiome -- 8.7.2 Microbiome Relevance in TEH -- 8.8 Pan-Omics in a TEH Model -- References -- Chapter 9 Silicone Wristbands and Wearables to Assess Chemical Exposures -- 9.1 Personal Chemical Exposures -- 9.2 Passive Sampling -- 9.2.1 Passive Sampling Background -- 9.2.2 Silicone Wristbands -- 9.3 Silicone Wristband Characterization -- 9.3.1 Wristband Advantages -- 9.3.2 Chemical Uptake -- 9.3.3 Wristband Data Applications.
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|a 9.3.4 Silicone Wristband Limitations and Additional Considerations -- 9.4 Laboratory Practices -- 9.4.1 Wristband Preparation and Shipment -- 9.4.2 Chemical Stability in Wristbands -- 9.4.3 Chemical Extraction -- 9.4.4 Chemical and Biological Analysis -- 9.5 Human Research Ethics -- 9.6 Silicone Wristband Applications -- 9.6.1 Initial Field Applications -- 9.6.2 Comparisons with Conventional Exposure Assessment Technologies -- 9.6.3 Health Effects -- 9.6.4 Additional Configurations of Silicone Wristbands -- 9.7 Future Directions -- 9.7.1 Chemical Mixtures -- 9.7.2 Disaster-Related Exposures -- 9.7.3 Behavioral Health Interventions -- 9.7.4 Precision Health and Precision Prevention -- Acknowledgments -- Conflict of Interest -- References -- Chapter 10 Total Exposure Hearing Health Preservation -- 10.1 Introduction -- 10.2 Overview of Hearing Health -- 10.3 Auditory and Non-Auditory Health Effects -- 10.4 Exposure Lifetime -- 10.5 Noise Type: Continuous and Impulse -- 10.6 Non-Noise Exposures -- 10.7 Genetics -- 10.8 How Do I Measure Risk? -- 10.9 How Do I Control Risk? -- 10.10 Conclusion -- References -- Chapter 11 The Role of Noise Exposure as an Element of Total Exposure Health: Determination of 24-Hour Noise Exposure Profiles on U.S. Navy Aircraft Carriers -- 11.1 Introduction -- 11.2 Noise Exposure on U.S. Navy Aircraft Carriers -- 11.3 Auditory Effects -- 11.4 Non-Auditory Effects -- 11.5 Regulation -- 11.6 24-Hour Noise Exposure Aboard U.S. Navy Aircraft Carriers (Schaal et al., 2019c) -- 11.7 Characterization of Extended Shift Noise Exposures among Low Noise Hazard U.S. Navy Aircraft Carrier Support Personnel (Schaal et al., 2019a) -- 11.8 Noise Characterization of "Effective Quiet" Areas on a U.S. Navy Aircraft Carrier (Schaal et al., 2019d) -- 11.9 Sound Level Measurements in Berthing Areas of an Aircraft Carrier (Schaal et al., 2019b).
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|a 11.10 Discussion.
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|a HS113 - Diploma in Enviromental Health
|z References
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| 588 |
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|a Description based on publisher supplied metadata and other sources.
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| 590 |
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|a Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2021. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
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| 650 |
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|a Health risk assessment.
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| 655 |
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|a Electronic books.
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| 700 |
1 |
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|a Yamamoto, Dirk P.
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| 700 |
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|a Racz, LeeAnn.
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| 776 |
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|i Print version:
|a Phillips, Kirk A.
|t Total Exposure Health : An Introduction
|d Milton : Taylor & Francis Group,c2020
|z 9780367201395
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| 797 |
2 |
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|a ProQuest (Firm)
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| 830 |
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|a Environmental and Occupational Health Ser.
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| 856 |
4 |
0 |
|u https://ezaccess.library.uitm.edu.my/login?url=https://ebookcentral.proquest.com/lib/uitm-ebooks/detail.action?docID=6201278
|z View fulltext via EzAccess
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| 966 |
0 |
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|a 2021
|b ProQuest Ebook Central
|c UiTM Library
|d Dr. Wan Ismahanisa Ismail
|e Faculty of Health Sciences
|f ProQuest
|