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|a 571.6
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|a Hardin, Jeff.
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|a Becker's World of the Cell, Global Edition.
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|a 9th ed.
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|a Harlow, United Kingdom :
|b Pearson Education, Limited,
|c 2017.
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|c ©2017.
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|a 1 online resource (922 pages)
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|a text
|b txt
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|a online resource
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|a Front Cover -- About the Authors -- Brief Contents -- Detailed Contents -- Preface -- Acknowledgments -- Chapter 1: A Preview of Cell Biology -- 1.1: The Cell Theory: A Brief History -- Advances in Microscopy Allowed Detailed Studies of Cells -- The Cell Theory Applies to All Organisms -- 1.2: The Emergence of Modern Cell Biology -- The Cytological Strand Deals with Cellular Structure -- The Biochemical Strand Studies the Chemistry of Biological Structure and Function -- The Genetic Strand Focuses on Information Flow -- 1.3: How Do We Know What We Know? -- Biological "Facts" May Turn Out to Be Incorrect -- Experiments Test Specific Hypotheses -- Model Organisms Play a Key Role in Modern Cell Biology Research -- Well-Designed Experiments Alter Only One Variable at a Time -- Summary of Key Points -- Problem Set -- Key Technique: Using Immunofluorescence to Identify Specific Cell Components -- Human Connections: The Immortal Cells of Henrietta Lacks -- Chapter 2: The Chemistry of the Cell -- 2.1: The Importance of Carbon -- Carbon-Containing Molecules Are Stable -- Carbon-Containing Molecules Are Diverse -- Carbon-Containing Molecules Can Form Stereoisomers -- 2.2: The Importance of Water -- Water Molecules Are Polar -- Water Molecules Are Cohesive -- Water Has a High Temperature-Stabilizing Capacity -- Water Is an Excellent Solvent -- 2.3: The Importance of Selectively Permeable Membranes -- A Membrane Is a Lipid Bilayer with Proteins Embedded in It -- Lipid Bilayers Are Selectively Permeable -- 2.4: The Importance of Synthesis by Polymerization -- Macromolecules Are Critical for Cellular Form and Function -- Cells Contain Three Different Kinds of Macromolecular Polymers -- Macromolecules Are Synthesized by Stepwise Polymerization of Monomers -- 2.5: The Importance of Self-Assembly.
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|a Noncovalent Bonds and Interactions Are Important in the Folding of Macromolecules -- Many Proteins Spontaneously Fold into Their Biologically Functional State -- Molecular Chaperones Assist the Assembly of Some Proteins -- Self-Assembly Also Occurs in Other Cellular Structures -- The Tobacco Mosaic Virus Is a Case Study in Self-Assembly -- Self-Assembly Has Limits -- Hierarchical Assembly Provides Advantages for the Cell -- Summary of Key Points -- Problem Set -- Key Technique: Determining the Chemical Fingerprint of a Cell Using Mass Spectrometry -- Human Connections: Taking a Deeper Look: Magnetic Resonance Imaging (MRI) -- Chapter 3: The Macromolecules of the Cell -- 3.1: Proteins -- The Monomers Are Amino Acids -- The Polymers Are Polypeptides and Proteins -- Several Kinds of Bonds and Interactions Are Important in Protein Folding and Stability -- Protein Structure Depends on Amino Acid Sequence and Interactions -- 3.2: Nucleic Acids -- The Monomers Are Nucleotides -- The Polymers Are DNA and RNA -- A DNA Molecule Is a Double-Stranded Helix -- 3.3: Polysaccharides -- The Monomers Are Monosaccharides -- The Polymers Are Storage and Structural Polysaccharides -- Polysaccharide Structure Depends on the Kinds of Glycosidic Bonds Involved -- 3.4: Lipids -- Fatty Acids Are the Building Blocks of Several Classes of Lipids -- Triacylglycerols Are Storage Lipids -- Phospholipids Are Important in Membrane Structure -- Glycolipids Are Specialized Membrane Components -- Steroids Are Lipids with a Variety of Functions -- Terpenes Are Formed from Isoprene -- Summary of Key Points -- Problem Set -- Human Connections: Aggregated Proteins and Alzheimer's -- Key Technique: Using X-Ray Crystallography to Determine Protein Structure -- Chapter 4: Cells and Organelles -- 4.1: Where Did the First Cells Come From?.
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|a Simple Organic Molecules May Have Formed Abiotically in the Young Earth -- RNA May Have Been the First Informational Molecule -- Liposomes May Have Defined the First Primitive Protocells -- 4.2: Properties and Strategies of Cells -- All Organisms Are Bacteria, Archaea, or Eukaryotes -- There Are Several Limitations on Cell Size -- Bacteria, Archaea, and Eukaryotes Differ from Each Other in Many Ways -- 4.3: The Eukaryotic Cell in Overview: Structure and Function -- The Plasma Membrane Defines Cell Boundaries and Retains Contents -- The Nucleus Is the Information Center of the Eukaryotic Cell -- Mitochondria and Chloroplasts Provide Energy for the Cell -- The Endosymbiont Theory Proposes That Mitochondria and Chloroplasts Were Derived From Bacteria -- The Endomembrane System Synthesizes Proteins for a Variety of Cellular Destinations -- Other Organelles Also Have Specific Functions -- Ribosomes Synthesize Proteins in the Cytoplasm -- The Cytoskeleton Provides Structure to the Cytoplasm -- The Extracellular Matrix and Cell Walls Are Outside the Plasma Membrane -- 4.4: Viruses, Viroids, and Prions: Agents That Invade Cells -- A Virus Consists of a DNA or RNA Core Surrounded by a Protein Coat -- Viroids Are Small, Circular RNA Molecules That Can Cause Plant Diseases -- Prions Are Infectious Protein Molecules -- Summary of Key Points -- Problem Set -- Human Connections: When Cellular "Breakdown" Breaks Down -- Key Technique: Using Centrifugation to Isolate Organelles -- Chapter 5: Bioenergetics: The Flow of Energy in the Cell -- 5.1: The Importance of Energy -- Cells Need Energy to Perform Six Different Kinds of Work -- Organisms Obtain Energy Either from Sunlight or from the Oxidation of Chemical Compounds -- Energy Flows Through the Biosphere Continuously -- The Flow of Energy Through the Biosphere Is Accompanied by a Flow of Matter.
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|a 5.2: Bioenergetics -- Understanding Energy Flow Requires Knowledge of Systems, Heat, and Work -- The First Law of Thermodynamics States That Energy Is Conserved -- The Second Law of Thermodynamics States That Reactions Have Directionality -- Entropy and Free Energy Are Two Means of Assessing Thermodynamic Spontaneity -- 5.3: Understanding ∆G and Keq -- The Equilibrium Constant Keq Is a Measure of Directionality -- ∆G Can Be Calculated Readily -- The Standard Free Energy Change Is ∆G Measured Under Standard Conditions -- Summing Up: The Meaning of ∆G´ and ∆G˚´ -- Free Energy Change: Sample Calculations -- Jumping Beans Provide a Useful Analogy for Bioenergetics -- Life Requires Steady-State Reactions That Move Toward Equilibrium Without Ever Getting There -- Summary of Key Points -- Problem Set -- Human Connections: The "Potential" of Food to Provide Energy -- Key Technique: Measuring How Molecules Bind to One Another Using Isothermal Titration Calorimetry -- Chapter 6: Enzymes: The Catalysts of Life -- 6.1: Activation Energy and the Metastable State -- Before a Chemical Reaction Can Occur, the Activation Energy Barrier Must Be Overcome -- The Metastable State Is a Result of the Activation Barrier -- Catalysts Overcome the Activation Energy Barrier -- 6.2: Enzymes as Biological Catalysts -- Most Enzymes Are Proteins -- Substrate Binding, Activation, and Catalysis Occur at the Active Site -- Ribozymes Are Catalytic RNA Molecules -- 6.3: Enzyme Kinetics -- Monkeys and Peanuts Provide a Useful Analogy for Understanding Enzyme Kinetics -- Most Enzymes Display Michaelis-Menten Kinetics -- What Is the Meaning of Vmax and Km? -- Why Are Km and Vmax Important to Cell Biologists? -- The Double-Reciprocal Plot Is a Useful Means of Visualizing Kinetic Data -- Enzyme Inhibitors Act Either Irreversibly or Reversibly -- 6.4: Enzyme Regulation.
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|a Allosteric Enzymes Are Regulated by Molecules Other than Reactants and Products -- Allosteric Enzymes Exhibit Cooperative Interactions Between Subunits -- Enzymes Can Also Be Regulated by the Addition or Removal of Chemical Groups -- Summary of Key Points -- Problem Set -- Human Connections: ACE Inhibitors: Enzyme Activity as the Difference Between Life and Death -- Key Technique: Determining Km and Vmax Using Enzyme Assays -- Chapter 7: Membranes: Their Structure, Function, and Chemistry -- 7.1: The Functions of Membranes -- Membranes Define Boundaries and Serve as Permeability Barriers -- Membranes Are Sites of Specific Proteins and Therefore of Specific Functions -- Membrane Proteins Regulate the Transport of Solutes -- Membrane Proteins Detect and Transmit Electrical and Chemical Signals -- Membrane Proteins Mediate Cell Adhesion and Cell-to-Cell Communication -- 7.2: Models of Membrane Structure: An Experimental Perspective -- Overton and Langmuir: Lipids Are Important Components of Membranes -- Gorter and Grendel: The Basis of Membrane Structure Is a Lipid Bilayer -- Davson and Danielli: Membranes Also Contain Proteins -- Robertson: All Membranes Share a Common Underlying Structure -- Further Research Revealed Major Shortcomings of the Davson-Danielli Model -- Singer and Nicolson: A Membrane Consists of a Mosaic of Proteins in a Fluid Lipid Bilayer -- Unwin and Henderson: Most Membrane Proteins Contain Transmembrane Segments -- Recent Findings Suggest Membranes Are Organized into Microdomains -- 7.3: Membrane Lipids: The "Fluid" Part of the Model -- Membranes Contain Several Major Classes of Lipids -- Fatty Acids Are Essential to Membrane Structure and Function -- Thin-Layer Chromatography Is an Important Technique for Lipid Analysis -- Membrane Asymmetry: Most Lipids Are Distributed Unequally Between the Two Monolayers.
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|a The Lipid Bilayer Is Fluid.
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|a For courses in cell biology.Explore the world of the cellWidely praised for its strong biochemistry coverage and clear, easy-to-follow explanations and figures, Becker's World of the Cell provides a beautifully-illustrated, up-to-date introduction to cell biology concepts, processes, and applications.Informed by many year.
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|a AS201 - Bachelor of Science (Hons.) Biology
|z Syllabus Programme
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| 588 |
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|a Description based on publisher supplied metadata and other sources.
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| 590 |
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|a Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2021. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
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| 655 |
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4 |
|a Electronic books.
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| 700 |
1 |
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|a Bertoni, Gregory Paul.
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| 700 |
1 |
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|a Kleinsmith, Lewis J.
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| 776 |
0 |
8 |
|i Print version:
|a Hardin, Jeff
|t Becker's World of the Cell, Global Edition
|d Harlow, United Kingdom : Pearson Education, Limited,c2017
|z 9781292177694
|
| 797 |
2 |
|
|a ProQuest (Firm)
|
| 856 |
4 |
0 |
|u https://ezaccess.library.uitm.edu.my/login?url=https://ebookcentral.proquest.com/lib/uitm-ebooks/detail.action?docID=5186065
|z View fulltext via EzAccess
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| 966 |
0 |
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|a 2021
|b ProQuest Ebook Central
|c UiTM Library
|d Mohd Fadhli Samsudin
|e Faculty of Applied Sciences
|f ProQuest
|