Drug Management of Prostate Cancer

This book is a comprehensive, concise summary of the pharmacological treatments of prostate cancer. It is an authoritative and up-to-date reference on therapeutic options involving both standard of care and investigational agents. The chapters describe state of the art information on Hormone Therapy...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Figg, William D. (Editor), Chau, Cindy H. (Editor), Small, Eric J. (Editor)
Format: Electronic
Language:English
Published: New York, NY : Springer New York : Imprint: Springer, 2010.
Subjects:
Online Access:https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-60327-829-4
Table of Contents:
  • Section One: Hormone Therapy
  • Cell Biology of Prostate Cancer and Molecular Targets
  • Luteinizing Hormone-Releasing Hormone (Lh-Rh) and its Agnostic, Antagonistic and Targeted Cytotoxic Analogs in Prostate Cancer
  • Nuclear Receptor Coregulators: Promising Therapeutic Targets for the Treatment of Prostate Cancer
  • Androgens and Prostate Cancer
  • Androgen Receptor Biology in Prostate Cancer
  • Androgen Receptor Antagonists
  • 5 alpha Reductase Inhibitors in Prostate Cancer
  • Adrenolytic Therapies in Castration Resistant Prostate Cancer
  • Androgen Deprivation Therapy
  • Pharmacogenetics of the Androgen Metabolic Pathway
  • Section Two: Chemotherapy
  • Mitoxantrone
  • Docetaxel
  • Beyond Docetaxel: Emerging Agents in the Treatment of Advanced Prostate Cancer
  • Platinum Agents in Prostate Cancer
  • Clinical Pharmacology and Pharmacogenetics of Chemotherapy in Prostate Cancer
  • Microtubule Targeting Agents
  • Section Three: Angiogenesis
  • Principles of Antiangiogenic Therapy
  • Bevacizumab in Advanced Prostate Cancer
  • Thalidomide and Analogs
  • Investigational Angiogenesis Inhibitors
  • Pharmacogenetics of Angiogenesis
  • Section Four: Bone Metastasis
  • Pathophysiology of Prostate Cancer Bone Metastasis
  • Radiopharmaceuticals
  • Bisphosphonates for Prevention and Treatment of Bone Metastases
  • Endothelin Receptors as Therapeutic Targets in Castrate Resistant Prostate Cancer
  • Calcitriol and Vitamin D Analogs
  • Cancer Immunology, Immunotherapeutics and Vaccine Approaches
  • Sipuleucel-T (APC8015): Active Cellular Immunotherapy for Advanced Metastatic Castrate-Resistant Prostate Cancer
  • GM-CSF Genes Transduced Prostate Cancer Vaccines: GVAX
  • CTLA-4 Blockade for Prostate Cancer Treatment
  • Section Five: Prevention
  • Prostate Cancer Chemoprevention Strategies
  • Diet and Prostate Cancer Incidence, Recurrence, and Progression Risk
  • Inflammation as a Target in Prostate Cancer
  • Section Six: Drug Development
  • Challenges for the Development of New Agents in Prostate Cancer
  • FDA Approval of Prostate Cancer Treatments
  • Applications of Proteomics in Prostate Cancer.