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130607s2010 xxu| s |||| 0|eng d |
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|a 9781603278294
|9 978-1-60327-829-4
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|a 10.1007/978-1-60327-829-4
|2 doi
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|a RC254-282
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|a MJCL
|2 bicssc
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|a MED062000
|2 bisacsh
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|a 616.994
|2 23
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|a Figg, William D.
|e editor.
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|a Drug Management of Prostate Cancer
|c edited by William D. Figg, Cindy H. Chau, Eric J. Small.
|h [electronic resource] /
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|a New York, NY :
|b Springer New York :
|b Imprint: Springer,
|c 2010.
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300 |
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|a XVII, 428p. 34 illus., 22 illus. in color.
|b online resource.
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a text file
|b PDF
|2 rda
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|a Section One: Hormone Therapy -- Cell Biology of Prostate Cancer and Molecular Targets -- Luteinizing Hormone-Releasing Hormone (Lh-Rh) and its Agnostic, Antagonistic and Targeted Cytotoxic Analogs in Prostate Cancer -- Nuclear Receptor Coregulators: Promising Therapeutic Targets for the Treatment of Prostate Cancer -- Androgens and Prostate Cancer -- Androgen Receptor Biology in Prostate Cancer -- Androgen Receptor Antagonists -- 5 alpha Reductase Inhibitors in Prostate Cancer -- Adrenolytic Therapies in Castration Resistant Prostate Cancer -- Androgen Deprivation Therapy -- Pharmacogenetics of the Androgen Metabolic Pathway -- Section Two: Chemotherapy -- Mitoxantrone -- Docetaxel -- Beyond Docetaxel: Emerging Agents in the Treatment of Advanced Prostate Cancer -- Platinum Agents in Prostate Cancer -- Clinical Pharmacology and Pharmacogenetics of Chemotherapy in Prostate Cancer -- Microtubule Targeting Agents -- Section Three: Angiogenesis -- Principles of Antiangiogenic Therapy -- Bevacizumab in Advanced Prostate Cancer -- Thalidomide and Analogs -- Investigational Angiogenesis Inhibitors -- Pharmacogenetics of Angiogenesis -- Section Four: Bone Metastasis -- Pathophysiology of Prostate Cancer Bone Metastasis -- Radiopharmaceuticals -- Bisphosphonates for Prevention and Treatment of Bone Metastases -- Endothelin Receptors as Therapeutic Targets in Castrate Resistant Prostate Cancer -- Calcitriol and Vitamin D Analogs -- Cancer Immunology, Immunotherapeutics and Vaccine Approaches -- Sipuleucel-T (APC8015): Active Cellular Immunotherapy for Advanced Metastatic Castrate-Resistant Prostate Cancer -- GM-CSF Genes Transduced Prostate Cancer Vaccines: GVAX -- CTLA-4 Blockade for Prostate Cancer Treatment -- Section Five: Prevention -- Prostate Cancer Chemoprevention Strategies -- Diet and Prostate Cancer Incidence, Recurrence, and Progression Risk -- Inflammation as a Target in Prostate Cancer -- Section Six: Drug Development -- Challenges for the Development of New Agents in Prostate Cancer -- FDA Approval of Prostate Cancer Treatments -- Applications of Proteomics in Prostate Cancer.
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|a This book is a comprehensive, concise summary of the pharmacological treatments of prostate cancer. It is an authoritative and up-to-date reference on therapeutic options involving both standard of care and investigational agents. The chapters describe state of the art information on Hormone Therapy, Chemotherapy, Angiogenesis, Therapy for Bone Metastases, Immunotherapy, Prevention, and Drug Development. Drug Management of Prostate Cancer is an excellent resource for medical oncologists, trainees, researchers, and members of the pharmaceutical industry
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|a Medicine.
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|a Internal medicine.
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|a Oncology.
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|a Urology.
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650 |
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4 |
|a Medicine & Public Health.
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650 |
2 |
4 |
|a Oncology.
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650 |
2 |
4 |
|a Urology/Andrology.
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650 |
2 |
4 |
|a Internal Medicine.
|
700 |
1 |
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|a Chau, Cindy H.
|e editor.
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700 |
1 |
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|a Small, Eric J.
|e editor.
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710 |
2 |
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|a SpringerLink (Online service)
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773 |
0 |
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|t Springer eBooks
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776 |
0 |
8 |
|i Printed edition:
|z 9781603278317
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856 |
4 |
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|u https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-60327-829-4
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912 |
# |
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|a ZDB-2-SME
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950 |
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|a Medicine (Springer-11650)
|