Regulation of microRNAs

Given this pervasiveness and importance of miRNA-mediated gene regulation, it should come as little surprise that miRNAs themselves are also highly regulated. However, the recent explosion of knowledge on this topic has been remarkable, providing a primary motivation for publication of this book. As...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Gro<U+00df>hans, Helge. (Editor)
Format: Electronic
Language:English
Published: New York, NY : Springer US, 2010.
Series:Advances in Experimental Medicine and Biology, 700
Subjects:
Online Access:https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-4419-7823-3
Description
Summary:Given this pervasiveness and importance of miRNA-mediated gene regulation, it should come as little surprise that miRNAs themselves are also highly regulated. However, the recent explosion of knowledge on this topic has been remarkable, providing a primary motivation for publication of this book. As miRNAs are transcribed by RNA polymerase II, the enzyme that also generates mRNAs, it was perhaps not unexpected that miRNA transcription would be subject to regulation, and we have willfully mitted this aspect from this monograph. However, what has been unexpected is the extent of post-transcriptional regulation of miRNAs that is illustrated in this book.
Physical Description:XVI, 160p. 35 illus., 6 illus. in color. online resource.
ISBN:9781441978233
ISSN:0065-2598 ;