Androgen Action in Prostate Cancer

• Corporate Author: SpringerLink (Online service)
• Other Authors: Mohler, James. (Editor), Tindall, Donald. (Editor)
• Format: Electronic
• Language: English
• Published: New York, NY : Springer US, 2009.
• Subjects: Medicine.; Oncology.; Human genetics.; Immunology.; Microbiology.; Toxicology.; Medical virology.; Biomedicine.; Cancer Research.; Human Genetics.; Medical Microbiology.; Pharmacology/Toxicology.; Virology.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-0-387-69179-4

This book serves as a tribute to the work of the many investigators who have attempted to understand the role of the androgen receptor (AR) in the development and progression of prostate cancer. The relationship between prostate cancer and androgen status was initially appreciated in the late 1800s...

Table of Contents:

• From the contents Introduction: History, Nomenclature, Topic and Author Selection, Goals and Objectives
• 1. The Role of Androgens in Development of the Normal Prostate and Progression of Prostate Cancer
• 2. Androgen Action and Modulation of Prostate and Prostate Cancer Growth: An Overview of Research in The Authors Laboratory
• 3. Clinical progression to castration-recurrent prostate cancer
• 4. Androgen Metabolism
• 5. Increased expression of genes converting adrenal androgens to testosterone in castration-recurrent prostate cancer
• 6. Androgen metabolic genes in prostate cancer predisposition and progression
• 7. Effect of Steroid 5a -Reductase Inhibitors on Markers of Tumor Regression and Proliferation in Prostate Cancer. 8. 5a-Reductase Isozymes in Castration-Recurrent Prostate Cancer
• 9. Androgen Receptor Structure/Function Relationships.