Tissue engineering of temporomandibular joint cartilage

The temporomandibular joint (TMJ) is a site of intense morbidity for millions of people, especially young, pre-menopausal women. Central to TMJ afflictions are the cartilaginous tissues of the TMJ, especially those of the disc and condylar cartilage, which play crucial roles in normal function of th...

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Bibliographic Details
Other Authors: Athanasiou, K. A.
Format: Electronic
Language:English
Published: San Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) : Morgan & Claypool Publishers, c2009.
Series:Synthesis lectures on tissue engineering (Online), # 2.
Subjects:
Online Access:Abstract with links to full text
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245 0 0 |a Tissue engineering of temporomandibular joint cartilage  |c Kyriacos A. Athanasiou ... [et al.].  |h [electronic resource] / 
260 # # |a San Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) :  |b Morgan & Claypool Publishers,  |c c2009. 
300 # # |a 1 electronic text (xi, 108 p. : ill.) :  |b digital file. 
490 1 # |a Synthesis lectures on tissue engineering,  |v # 2  |x 1944-0308 ; 
500 # # |a Part of: Synthesis digital library of engineering and computer science. 
500 # # |a Title from PDF t.p. (viewed on July 8, 2009). 
500 # # |a Series from website. 
504 # # |a Includes bibliographical references (p. 71-105). 
505 0 # |a The temporomandibular joint -- Tissue engineering -- Anatomy and physiology of the temporomandibular joint -- Development -- Etiology, the TMJ healing problem, and age related changes -- Pathophysiology, catabolism, and osteoarthrosis -- Guidelines for testing and modeling of tissue mechanics -- The biomechanical environment of the TMJ -- Animal models -- Current therapies -- Non-invasive treatments -- Minimally invasive treatments -- TMJ surgical therapies -- Invasive surgical therapies, total joint replacement -- TMJ repair using alloplastic devices -- Past experiences -- Currently approved therapies -- Immune response, immunogenicity, transplants -- Gender paradox -- Fibrocartilage of the TMJ disc -- Introduction -- Anatomy: structure and attachments -- Biochemical content -- Collagen composition and distribution -- Collagen organization -- Elastin -- Proteoglycans and glycosaminoglycans -- Biomechanical properties -- Tensile properties -- Compressive properties -- Shear and frictional properties -- Cell types -- Age-associated changes in the disc -- Cartilage of the mandibular condyle -- Introduction -- Biochemical content -- Collagen composition and distribution -- Collagen organization -- Proteoglycans and glycosaminoglycans -- Biomechanical properties -- Tensile and shear properties -- Compressive properties -- Cell content -- Tissue engineering of the disc -- Introduction -- Previous tissue engineering efforts -- Scaffolds -- Bioactive agents -- Mechanical stimulation and bioreactors -- Tissue engineering of the mandibular condyle -- Introduction -- Cells of the mandibular condylar cartilage -- Mandibular condyle tissue engineering studies -- Current perspectives -- Cell sources for tissue engineering of cartilage -- Primary cells -- Stem cells -- The joint capsule and the synovium -- Design standards for tissue engineering -- Assessments of tissue engineered constructs -- Directions to improve patient outcomes -- Bibliography -- Biography. 
506 # # |a Abstract freely available; full-text restricted to subscribers or individual document purchasers. 
510 0 # |a Compendex 
510 0 # |a INSPEC 
510 0 # |a Google scholar 
510 0 # |a Google book search 
520 3 # |a The temporomandibular joint (TMJ) is a site of intense morbidity for millions of people, especially young, pre-menopausal women. Central to TMJ afflictions are the cartilaginous tissues of the TMJ, especially those of the disc and condylar cartilage, which play crucial roles in normal function of this unusual joint. Damage or disease to these tissues significantly impacts a patient's quality of life by making common activities such as talking and eating difficult and painful. Unfortunately, these tissues have limited ability to heal, necessitating the development of treatments for repair or replacement. The burgeoning field of tissue engineering holds promise that replacement tissues can be constructed in the laboratory to recapitulate the functional requirements of native tissues. This book outlines the biomechanical, biochemical, and anatomical characteristics of the disc and condylar cartilage, and also provides a historical perspective of past and current TMJ treatments and previous tissue engineering efforts. This book was written to serve as a reference for researchers seeking to learn about the TMJ, for undergraduate and graduate level courses, and as a compendium of TMJ tissue engineering design criteria. 
530 # # |a Also available in print. 
538 # # |a Mode of access: World Wide Web. 
538 # # |a System requirements: Adobe Acrobat reader. 
650 # 0 |a Temporomandibular joint  |x Diseases  |x Treatment. 
650 # 0 |a Tissue engineering. 
650 # 0 |a Artificial temporomandibular joints. 
690 # # |a Temporomandibular joint 
690 # # |a Tissue engineering 
690 # # |a TMJ disc 
690 # # |a Mandibular condyle 
690 # # |a Cartilage 
690 # # |a Fibrocartilage 
690 # # |a Temporomandibular joint dysfunction (TMD) 
690 # # |a Chondrocyte 
690 # # |a Fibrochondrocyte 
690 # # |a Biomechanics 
700 1 # |a Athanasiou, K. A.  |q (Kyriacos A.) 
730 0 # |a Synthesis digital library of engineering and computer science. 
830 # 0 |a Synthesis lectures on tissue engineering (Online),  |v # 2.  |x 1944-0308 ; 
856 4 2 |u https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.2200/S00198ED1V01Y200906TIS002  |3 Abstract with links to full text