The Chaperonopathies Diseases with Defective Molecular Chaperones /

• Main Authors: Macario, Alberto J.L. (Author), Conway de Macario, Everly. (Author), Cappello, Francesco. (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic
• Language: English
• Published: Dordrecht : Springer Netherlands : Imprint: Springer, 2013.
• Series: SpringerBriefs in Biochemistry and Molecular Biology,
• Subjects: Medicine.; Biochemistry.; Biomedicine.; Biomedicine general.; Biochemistry, general.; Protein Science.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-94-007-4667-1

Memory lapses and occasional incoherent behavior, or intestinal cramps with diarrhea, or protracted cough with low fever, or cardiovascular syndromes, or changes in the pattern of movement of the lower limps, can be signs of an incipient chaperonopathy. Yet many physicians do not know this. Most hea...

Table of Contents:

• Overview and book plan
• Chaperones: General characteristics and classifications
• The chaperonopathies: classification, mechanisms, structural features
• Structural and hereditary chaperonopathies: mutation
• Other genetic chaperonopathies
• Acquired chaperonopathies
• Other types of chaperonopathies
• Impact of chaperonopathies in protein homeostasis and beyond
• Extracellular chaperones.