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130411s2013 ne | s |||| 0|eng d |
| 020 |
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|a 9789400746671
|9 978-94-007-4667-1
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|a 10.1007/978-94-007-4667-1
|2 doi
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|a R-RZ
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|a Macario, Alberto J.L.
|e author.
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|a The Chaperonopathies
|b Diseases with Defective Molecular Chaperones /
|c by Alberto J.L. Macario, Everly Conway de Macario, Francesco Cappello.
|h [electronic resource] :
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| 264 |
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|a Dordrecht :
|b Springer Netherlands :
|b Imprint: Springer,
|c 2013.
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| 300 |
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|a XVI, 116 p. 26 illus., 23 illus. in color.
|b online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 347 |
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|a text file
|b PDF
|2 rda
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| 490 |
1 |
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|a SpringerBriefs in Biochemistry and Molecular Biology,
|x 2211-9353
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| 505 |
0 |
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|a Overview and book plan -- Chaperones: General characteristics and classifications -- The chaperonopathies: classification, mechanisms, structural features -- Structural and hereditary chaperonopathies: mutation -- Other genetic chaperonopathies -- Acquired chaperonopathies -- Other types of chaperonopathies -- Impact of chaperonopathies in protein homeostasis and beyond -- Extracellular chaperones.
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| 520 |
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|a Memory lapses and occasional incoherent behavior, or intestinal cramps with diarrhea, or protracted cough with low fever, or cardiovascular syndromes, or changes in the pattern of movement of the lower limps, can be signs of an incipient chaperonopathy. Yet many physicians do not know this. Most health care professionals are unfamiliar with chaperonopathies. Clinicians do not look for them because they are unaware of them. Pathologists and clinical biochemists are unprepared to test specimens to detect chaperonopathies. Despite the large amount of information available in the literature, textbooks tend to ignore chaperonopathies. Because of the lack of systematic information in textbooks and courses, chaperonopathies are invisible to practitioners and clinical researchers. This book aims to correct this situation by providing pertinent information in an orderly manner so as to prompt the reader to look for chaperonopathies in patients and seek more information about them. The book serves as an alert signal and as a primer.
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| 650 |
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|a Medicine.
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| 650 |
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|a Biochemistry.
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| 650 |
1 |
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|a Biomedicine.
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| 650 |
2 |
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|a Biomedicine general.
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| 650 |
2 |
4 |
|a Biochemistry, general.
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| 650 |
2 |
4 |
|a Protein Science.
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| 700 |
1 |
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|a Conway de Macario, Everly.
|e author.
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| 700 |
1 |
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|a Cappello, Francesco.
|e author.
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| 710 |
2 |
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|a SpringerLink (Online service)
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| 773 |
0 |
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|t Springer eBooks
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| 776 |
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8 |
|i Printed edition:
|z 9789400746664
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| 830 |
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|a SpringerBriefs in Biochemistry and Molecular Biology,
|x 2211-9353
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| 856 |
4 |
0 |
|u https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-94-007-4667-1
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| 912 |
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|a ZDB-2-SBL
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| 950 |
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|a Biomedical and Life Sciences (Springer-11642)
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