Lead-Seeking Approaches

• Corporate Author: SpringerLink (Online service)
• Other Authors: Hayward, Matthew M. (Editor)
• Format: Electronic
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2010.
• Series: Topics in Medicinal Chemistry, 5
• Subjects: Chemistry.; Neurosciences.; Chemistry, Organic.; Biochemistry.; Medicinal Chemistry.; Organic Chemistry.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-3-642-01075-0

Christopher A. Lipinski: Overview of Hit to Lead: The Medicinal Chemists Role from HTS Retest to Lead Optimization Hand Off Jeff W. Paslay " John E. Morin " Richard K. Harrison: High Throughput Screening in the Twenty - First Century Jack Andrew Bikker " Lakshmi S.Narasimhan: Lead Di...

Table of Contents:

• Christopher A. Lipinski: Overview of hit to lead: the medicinal chemists role from HTS retest to lead optimization hand off
• Jeff W. Paslay; John E. Morin; Richard K. Harrison: High Throughput Screening in the 21st Century
• Jack Andrew Bikker; Lakshmi S.Narasimhan: Lead Discovery Using Virtual Screening
• Maurizio Pellecchia: NMR Spectroscopy in Fragment Based Drug Design
• Kevin D. Freeman-Cook; Daniel W. Kung: Hit Triage  Medicinal Chemistry Strategies to Improve the Odds of Success in Discovery
• John W. Ellingboe; Adam M. Gilbert: Lead Identification.