Gene Therapy for Autoimmune and Inflammatory Diseases

This book addresses the latest advances in viral and non-viral vectors, novel targets and methods for the treatment of autoimmune and inflammatory disease with a main focus in pre-clinical testing with up to date clinical trials. The first section of the book deals with current research approaches f...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Chernajovsky, Yuti. (Editor), Robbins, Paul D. (Editor)
Format: Electronic
Language:English
Published: Basel : Springer Basel, 2010.
Series:Milestones in Drug Therapy
Subjects:
Online Access:https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-3-0346-0165-8
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505 0 # |a From the contents: Rheumatoid arthritis -- Crohn's disease/IBD -- Diabetes -- Cystic fibrosis -- Multiple sclerosis -- Myositis -- Osteoarthritis -- Sjg̲rens syndrome -- Lupus -- New developments in vectors:Regulated promoters -- AAV Vectors -- Plasmid delivery -- Gutted adenovirus -- Cells as carriers of gene therapy including stem cells -- Perspectives for the future developments of gene therapy for autoimmune and inflammatory therapy. 
520 # # |a This book addresses the latest advances in viral and non-viral vectors, novel targets and methods for the treatment of autoimmune and inflammatory disease with a main focus in pre-clinical testing with up to date clinical trials. The first section of the book deals with current research approaches for treating rheumatoid arthritis, osteoarthritis, diabetes, Crohn's disease, multiple sclerosis, Sjg̲rens syndrome, cystic fibrosis, myositis and lupus. The second section is devoted to cell delivery and vector development including plasmids, regulated promoters, adenovirus gutted vectors and adeno-associated vectors. All chapters are summarised by leaders in these fields. A must read for post graduate students, clinical and non-clinical researchers in the disciplines of immunology, molecular medicine, pharmacology, gene and cell-mediated therapy. 
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