BLyS Ligands and Receptors

The BLyS/BAFF family of cytokines and receptors has captured and held the attention of B cell biologists during the last decade. Discovery of the two ligands and three receptors comprising this family has yielded a watershed of insights; fostering fresh paradigms in our views about the differentiati...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Cancro, Michael P. (Editor)
Format: Electronic
Language:English
Published: Totowa, NJ : Humana Press, 2010.
Series:Contemporary Immunology
Subjects:
Online Access:https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-60327-013-7
Table of Contents:
  • The beautiful structures of BAFF, APRIL and their receptors
  • BAFF Receptor Regulation of Peripheral B Lymphocyte Survival and Development
  • Regulation of B cell self-tolerance by BAFF and the molecular basis of its action
  • Role of BAFF and APRIL in antibody production and diversification
  • Signal Transduction by receptors for BAFF and APRIL
  • TACI Signaling and Its Role in Immunity
  • The BAFF/APRIL System in Autoimmunity
  • Systemic immune-based rheumatic diseases: blissless states of BLySfulness
  • The role of BAFF and APRIL in regulating human B-cell behaviour: implications for disease pathogenesis
  • Translation of BAFF inhibition from mouse to non-human primate and human
  • BLyS/BR3 receptor signaling in the biology and pathophysiology of aggressive B cell lymphomas
  • Tipping the scales of survival: The role of BLyS in B-cell malignancies.