Post-Transcriptional Regulation by STAR Proteins Control of RNA Metabolism in Development and Disease /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Volk, Talila. (Editor), Artzt, Karen. (Editor)
• Format: Electronic
• Language: English
• Published: Boston, MA : Springer US, 2010.
• Series: Advances in Experimental Medicine and Biology, 693
• Subjects: Medicine.; Neurosciences.; Toxicology.; Biomedicine.; Pharmacology/Toxicology.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-4419-7005-3

This book aims to bring to the forefront a field that has been developing since the late 1990s called the STAR pathway for Signal Transduction and Activation of RNA. It is a signaling pathway that targets RNA directly; in contrast to the canonical signalkinase cascadetranscription factorDNARNA....

Table of Contents:

• STAR TREK: An Introduction to STAR Family Proteins and Review of QKI
• THE STAR FAMILY MEMBER: QUAKING (QKI) AND CEL SIGNALING
• INSIGHTS INTO THE STRUCTURAL BASIS OF RNA RECOGNITION BY STAR DOMAIN PROTEINS
• Posttranslat ional Regulat ion of STAR Proteins and Effects on Their Biological Functions
• EXPRESSION AND FUNCTIONS OF THE star PROTEINS Sam68 AND tstar IN MAMMALIAN SPERMATOGENESIS
• The role of quaking in mammalian embryonic development
• Drosophila STAR Proteins: What Can Be Learned from Flies?
• C. ELEGANS STAR PROTEINS, GLD1 AND ASD2, REGULATE SPECIFIC RNA TARGETS TO CONTROL DEVELOPMENT
• THE BRANCHPOINT BINDING PROTEIN: In and Out of the Spliceosome Cycle
• Reaching for the Stars: Linking Rna Binding Proteins to Diseases.