Vascular Disruptive Agents for the Treatment of Cancer
Tumour survival and growth is critically dependent on an independent blood supply. As such tumour vasculature presents an ideal target for cancer therapy that is widely applicable, accessible and genetically stable rendering it less prone to resistance. Two approaches have been explored for cancer t...
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Format: | Electronic |
Language: | English |
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New York, NY :
Springer New York : Imprint: Springer,
2010.
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Online Access: | https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-4419-6609-4 |
Table of Contents:
- Introduction D Chaplin/ GR Pettit
- Pre-clinical development
- Target identification D Neri/A Harris
- Animal models RB Pedley/ G Tozer
- Combination therapy R Giavazzi / R Kerbel
- Biomarkers
- MRI A Padhani
- CT E Aboagye
- Ultrasound R Brekken
- Circulating endothelial cells F Bertolini
- Circulating tumour cells
- Serum markers
- Clinical development
- Combretastatin G Rustin
- DMXAA B Baguley
- Other agents
- Combination therapy Siemann D
- Conclusion.