The Role of Genetics in Breast and Reproductive Cancers
Of all factors contributing to breast cancer, family history of disease is the most powerful. Currently, our understanding of genetic predisposition to breast cancer includes three classes of genes as defined by their associated risks. BRCA1 and BRCA2 are high-penetrance breast cancer predisposition...
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| Format: | Electronic |
| Language: | English |
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New York, NY :
Springer New York,
2010.
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| Series: | Cancer Genetics
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| Online Access: | https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-4419-0477-5 |
Table of Contents:
- Recognition of Hereditary Breast and Reproductive Cancer Syndromes
- Cancer genetics in the clinic: The challenges and responsibilities of counseling women at risk
- Hereditary Breast and Ovarian Cancer Syndrome
- Modifiers of risk of hereditary breast and ovarian cancer
- Recent advances in under standing the cellular functions of BRCA1 and BRCA2
- Other hereditary breast and ovarian cancer syndromes and their genes
- Endometrial and ovarian cancer in patients with HNPCC Syndrome
- Somatic alterations and implications in breast epithelial cells
- Somatic alterations and implications in ovarian epithelial cells
- High frequency low penetrance alleles
- Host and viral genetics and risk of cervical cancer
- Estrogen metabolizing gene polymorphisms, genetic susceptibility, and pharmacogenomics
- The future of discoveries in breast and reproductive cancers: the genome and epigenetics.