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Acute Neuronal Injury The Role of Excitotoxic Programmed Cell Death Mechanisms /

This book is the result of a convergence of scientific information regarding mechanisms that produce acute nerve cell death in the brain. Although seemingly disparate, stroke, brain and spinal cord trauma, coma from a low serum glucose concentration (hypoglycemia), and prolonged epileptic seizures h...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Fujikawa, Denson G. (Editor)
Format: Electronic
Language:English
Published: Boston, MA : Springer US, 2010.
Subjects:
Medicine.
Neurosciences.
Neurology.
Pathology.
Psychiatry.
Cytology.
Neurobiology.
Biomedicine.
Cell Biology.
Online Access:View fulltext via EzAccess
Table of Contents:
  • Introduction: Programmed mechanisms and the clinical spectrum of excitotoxic neuronal death; D.G. Fujikawa
  • Part 1: Caspase-independent programmed cell death: general considerations. 1: Caspase-independent cell death mechanisms in simple animal models; M. Rieckher, N. Tavernarakis. 2: Programmed necrosis: a "new" cell death outcome for injured adult neurons?; S. Krantic, S.A. Susin. 3: Age-dependence of neuronal apoptosis and of caspase activation; D.G. Fujikawa. 4: Excitotoxic programmed cell death involves caspase-independent mechanisms; Ho Chul Kang, T.M. Dawson, V.L. Dawson
  • Part 2: Focal Cerebral ischemia. 5: Apoptosis-inducing factor translocation to nuclei in focal cerebral ischemia; C. Culmsee, N. Plesnila. 6: The role of poly(ADP-ribose) polymerase-1 (PARP-1) activation in focal cerebral ischemia; G. Faraco, A. Chiarugi
  • Part 3: Transient Global Ischemia. 7: Transient global cerebral ischemia produces necrotic, not apoptotic neurons; F. Colbourne, R. Auer. 8: Apoptosis-inducing factor translocation to nuclei after transient global ischemia; Can Liu, A.P. Signore, Guodong Cao, Jun Chen. 9: Role of æ-calpain I and lysosomal cathepsins in hippocampal neuronal necrosis after transient global ischemia in primates; A.B. Tonchev, T. Yamashima
  • Part 4: Traumatic central nervous system; CNS) injury. 10: Mitochondrial damage in traumatic CNS injury; L.M. Davis, P.G. Sullivan. 11: Programmed mechanisms in traumatic CNS injury; B.A. Stoica, A.I. Faden
  • Part 5: Hypoglycemic neuronal death. 12: Hypoglycemic neuronal death: morphological considerations; tentative title pending receipt of manuscript; R. Auer. 13: The role of poly(ADP-ribose) polymerase-1 (PARP-1) in hypoglycemic neuronal death; tentative title pending receipt of manuscript; Sang Won Suh, R.A. Swanson
  • Part 6: Seizure-induced neuronal death. 14: p53 activation is necessary in seizure-induced neuronal death; Zhiquin Tan, S.S. Schreiber. 15: DNA damage and repair in the brain: implications for seizure-induced neuronal injury, endangerment, and neuroprotection; S.L. Crowe, A.D. Kondratyev. 16: Activation of caspase-independent programmed pathways in seizure-induced neuronal necrosis; D.G. Fujikawa
  • Concluding Remarks; D.G. Fujikawa.

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