Modern Molecular Biology Approaches for Unbiased Discovery in Cancer Research /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Yegnasubramanian, Srinivasan. (Editor), Isaacs, William B. (Editor)
• Format: Electronic
• Language: English
• Published: New York, NY : Springer New York : Imprint: Springer, 2010.
• Series: Applied Bioinformatics and Biostatistics in Cancer Research
• Subjects: Medicine.; Oncology.; Human genetics.; Medical laboratories.; Microbiology.; Medical virology.; Biomedicine.; Cancer Research.; Human Genetics.; Laboratory Medicine.; Medical Microbiology.; Molecular Medicine.; Virology.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-0-387-69745-1

A convergence of advancements in molecular biology, engineering, computer science, biostatistics and other disciplines has made possible the development of technologies facilitating the massively parallel investigation of the complex biological phenomena driving cancer initiation and progression. Su...

Table of Contents:

• Genome sequencing
• Examining copy number changes
• Genomic sequence variation
• DNA protein interactions
• DNA methylation changes
• SAGE and other signal sequencing technologies
• Gene expression microarray technologies
• RNA interference and regulatory RNAs
• Protein microarrays
• Mass Spectrometry in proteomics.