Acute Myelogenous Leukemia Genetics, Biology and Therapy /
Acute myelogenous leukemia (AML), is the most common form of leukemia in adults. AML is a deadly form of malignancy, the prognosis for which has not improved in the last two decades. More importantly, it is a malignancy that is seen in older adults, therefore the number of cases is likely to rise as...
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| Format: | Electronic |
| Language: | English |
| Published: |
New York, NY :
Springer New York,
2010.
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| Edition: | 1. |
| Series: | Cancer Treatment and Research,
145 |
| Subjects: | |
| Online Access: | View fulltext via EzAccess |
Table of Contents:
- The Leukemia Stem Cell
- Epigenetic Mechanisms in AML - a Target for Therapy
- Chromosomal Translocations in AML: Detection and Prognostic Significance
- Chromosomal Deletions in AML
- Genes Predictive of Outcome and Novel Molecular Classification Schemes in Adult Acute Myeloid Leukemia
- Receptor Tyrosine Kinase Alterations in AML <U+0013> Biology and Therapy
- Lineage Specific Transcription Factor Aberrations in AML
- Pro-leukemic RUNX1 and CBF<U+00df> Mutations in the Pathogenesis of Acute Leukemia
- Acute Myeloid Leukemia with Mutated Nucleophosmin (NPM1): Molecular, Pathological and Clinical Features
- MicroRNAs: New Players in AML Pathogenesis
- Murine Models of Human Acute Myeloid Leukemia
- AML and Apoptosis
- Acute Promyelocytic Leukemia, a Paradigm for Differentitation Therapy
- Immunotherapy of AML
- Therapy of Acute Myelogenous Leukemia in Adults.