Multiple Primary Malignancies

• Main Author: Renda, Andrea. (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic
• Language: English
• Published: Milano : Springer Milan, 2009.
• Series: Updates in Surgery
• Subjects: Medicine.; Oncology.; Human genetics.; Surgery.; Abdomen > Surgery.; Medicine & Public Health.; Cancer Research.; Human Genetics.; Medicine/Public Health, general.; Abdominal Surgery.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-88-470-1095-6

Two to three decades ago, multiple primary malignancies (MPM) were considered to be simply a clinical curiosity, with sporadic reports, mostly single case descriptions, found in the literature. While in the last few years, analyses of larger series have been published, the number of cases has still...

Table of Contents:

• Introduction
• Nosography
• Epidemiology
• Carcinogenesis
• Iatrogenic multiple tumours (chemo- and radio-inducted)
• Immunodeficiency and MMT
• MMT and HPV infections: Pathology Depts experience about MMT
• Hereditary codified syndromes
• Multifocal tumours and multiple tumours
• Hereditary and familial ovarian breast cancer
• Hereditary syndromes: the experience of the University of Siena
• Sporadic colo-rectal tumours and MMT
• MMT not-codified syndromes
• Laboratory for MMT at-risk patients
• Role of advanced endoscopy to identify synchronous and metachronous tumours
• Imaging technique for synchronous tumours
• Hereditary syndromes: DNA-guided therapeutic implications
• Role of chemoprevention
• Conclusion.