Erythropoietins, Erythropoietic Factors, and Erythropoiesis Molecular, Cellular, Preclinical, and Clinical Biology /

This second edition is a one-source guide to current information about red blood cell physiology and the action of native and recombinant human erythropoietic factors. Topics in the fields of erythropoiesis, recombinant protein discovery and production, and treatment of patients with anemia due to r...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Elliott, Steven G. (Editor), Foote, Mary Ann. (Editor), Molineux, Graham. (Editor)
Format: Electronic
Language:English
Published: Basel : Birkhũser Basel, 2009.
Edition:2nd Revised and Extended Edition.
Series:Milestones in Drug Therapy
Subjects:
Online Access:https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-3-7643-8698-6
Table of Contents:
  • Erythropoiesis: an overview
  • Regulation of endogenous erythropoietin production
  • Biology of erythropoietin
  • Erythropoiesis - genetic abnormalities
  • Studies of erythropoiesis and the discovery and cloning of recombinant human erythropoietin.-Commercial production of recombinant erythropoietins
  • Biosimilar epoetins
  • New molecules and formulations
  • Structural basis for the signal transduction of erythropoietin
  • Intracellular signaling by the erythropoietin receptor
  • Mechanism of erythropoietin receptor activation
  • Pharmacokinetics of erythropoiesis-stimulating agents
  • Use of erythropoietic stimulating agents in the setting of renal disease
  • Abuse of recombinant erythropoietins and blood products by athletes
  • Role and regulation of iron metabolism in erythropoiesis and disease
  • Nonhematopoietic effects of erythropoiesis-stimulating agents.