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Recent Advances in Transthyretin Evolution, Structure and Biological Functions

There is a strong interest in transthyretin (TTR) in connection with protein evolution, medical and clinical research. Thus, this is an exciting time for experts in TTR research to come together to write a monograph covering both the basic and the clinical research into TTR. Transthyretin is a prote...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Richardson, Samantha J. (Editor), Cody, Vivian. (Editor)
Format: Electronic
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2009.
Subjects:
Medicine.
Human physiology.
Endocrinology.
Proteomics.
Biomedicine.
Human Physiology.
Online Access:https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-3-642-00646-3
Table of Contents:
  • Mechanisms of Molecular Recognition: Structural Characteristics of Transthyretin Ligand Interactions
  • TTR Synthesis During Development and Evolution: what the Marsupials Revealed
  • Evolution of Transthyretin Gene Structure
  • Evolutionary Insights from Fish Transthyretin
  • The Salmonella sp. TLP: a Periplasmic 5-hydroxyisourate Hydrolase
  • Vertebrate HIU Hydrolase - Identification, Function, Structure and Evolutionary Relationship with Transthyretin
  • Transthyretin-related and transthyretin-like proteins
  • The Transthyretin-Retinol-Binding Protein Complex
  • TTR and RBP: Implications in Fish Physiology
  • TTR and Endocrine Disruptors
  • Clinical Implications of TTR Amyloidosis
  • Molecular Pathogenesis Associated with Familial Amyloidotic Polyneuropathy
  • Histidine 31: The Achilles heel of Human Transthyretin. Microheterogeneity is not Enough to Understand the Molecular Causes of Amyloidogenicity
  • New Therapeutic Approaches for Familial Amyloidotic Polyneuropathy (FAP)
  • Liver Transplantation for Transthyretin Amyloidosis
  • Mouse Models of Transthyretin Amyloidosis
  • What have we learned from TTR-null mice: novel functions for TTR?- Transthyretin Null Mice: Developmental Phenotypes
  • TTR Null Mice as a Model to Study the Involvement of TTR in Neurobiology: from Neuropeptide Processing to Nerve Regeneration
  • Plasma Transthyretin Reflects the Fluctuations of Lean Body Mass in Health and Disease.

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