Genome sequencing technology and algorithms

• Other Authors: Kim, Sun, 1962-, Tang, Haixu., Mardis, Elaine, 1962-
• Format: Electronic
• Language: English
• Published: Boston : Artech House, c2008.
• Subjects: Genomes > Analysis.; Nucleotide sequence.; SCIENCE > Genetics & Genomics. > Life Sciences; Oligonucleotide Array Sequence Analysis > Laboratory Manuals.; Base Sequence > Laboratory Manuals.; Genetic Techniques > Laboratory Manuals.; Genome > Laboratory Manuals.; Génomes > Analyse.; Génome humain > Séquençage.; Génomique > Informatique.; Electronic books.
• Online Access: View fulltext via EzAccess; ebrary

"From a who's who of pioneers in the field comes a unique resource covering the latest advances in next generation genome sequencing and assembly. This groundbreaking book includes non-conventional techniques that are paving the way to potential new biomedical applications. Practitioners f...

Table of Contents:

• An overview of new DNA sequencing technology
• Array-based pyrosequencing technology
• The role of resequencing arrays in revolutionizing DNA sequencing
• Polony sequencing
• Genome sequencing: a complex path to personalized medicine
• Overview of genome assembly techniques
• Fragment assembly algorithms
• Assembly for double-ended short read sequencing technologies
• Genome characterization in the post-human genome project era
• The haplotyping problem: an overview of computational models and solutions
• Analysis of genomic alterations in cancer
• High-throughput assessments of epigenomics in human disease
• Comparative sequencing, assembly, and anchoring.