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Vaccines for Pandemic Influenza

Recent years have seen unprecedented outbreaks of avian influenza A viruses. In particular, highly pathogenic H5N1 viruses have not only resulted in widespread outbreaks in domestic poultry, but have been transmitted to humans resulting in numerous fatalities. The rapid expansion in their geographic...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Compans, Richard W. (Editor), Orenstein, Walter A. (Editor)
Format: Electronic
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2009.
Series:Current Topics in Microbiology and Immunology, 333
Subjects:
Medicine.
Immunology.
Toxicology.
Medical virology.
Biomedicine.
Virology.
Pharmacology/Toxicology.
Public Health/Gesundheitswesen.
Online Access:https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-3-540-92165-3
Table of Contents:
  • Preface
  • Pandemic influenza as a current threat
  • Designing vaccines for pandemic influenza
  • Current vaccines for seasonal influenza
  • Generation and characterization of candidate vaccine viruses for pre-pandemic influenza vaccines
  • Recombinant proteins produced in insect cells
  • Adjuvants for pandemic influenza vaccines
  • Live attenuated vaccines for pandemic influenza
  • Influenza vaccines for avian species
  • Development and application of avian influenza vaccines in China
  • Attenuated influenza virus vaccines with modified NS1 proteins
  • DNA Vaccines against Influenza viruses
  • Influenza neuraminidase as a vaccine antigen
  • Recombinant vectors as influenza vaccines
  • Universal Pandemic Influenza Vaccines
  • Influenza virus-like particles as pandemic vaccines
  • Antigenic cross-reactivity among H5N1 viruses
  • Transcutaneous immunization with influenza vaccines
  • Self-administered microneedle patches for pandemic influenza
  • Animal models for evaluation of influenza vaccines
  • Immunosenescence and influenza vaccine efficacy
  • Summary of recent clinical trials
  • Considerations for licensure of pandemic and pre-pandemic indications in the U.S.
  • Strategies for Broad Global Access to Pandemic Influenza Vaccines
  • Prioritization of Pandemic Influenza Vaccine: Rationale and Strategy for Decision-Making
  • Subject index.

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