Marine Toxins as Research Tools

• Corporate Author: SpringerLink (Online service)
• Other Authors: Fusetani, Nobuhiro. (Editor), Kem, William. (Editor)
• Format: Electronic
• Language: English
• Published: Berlin, Heidelberg : Springer Berlin Heidelberg, 2009.
• Series: Progress in Molecular and Subcellular Biology, 46
• Subjects: Chemistry.; Toxicology.; Biotechnology.; Environmental Engineering/Biotechnology.; Pharmacology/Toxicology.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-3-540-87895-7

Marine organisms produce a wide array of toxins, many of which are not only structurally unusual, but also show potent and interesting modes of action. Since the discovery of tetrodotoxin, a pufferfish toxin, as a potent and selective blocker of Na+ channels in 1964, it has been widely used as a res...

Table of Contents:

• Marine Toxins: An Overview
• Conotoxins: Molecular and Therapeutic Targets
• Sodium Channel Inhibiting Marine Toxins
• Sea Anemone Inhibitors of Potassium Channels
• Ligands for Ionotropic Glutamate Receptors
• Marine Toxins Potently Affecting Neurotransmitter Release1
• Toxins Affecting Actin Filaments and Microtubules
• Carcinogenic Aspects of Protein Phosphatase 1 and 2A Inhibitors.-.