Birth, Life and Death of Dopaminergic Neurons in the Substantia Nigra
This book provides a unique and timely multidisciplinary synthesis of our current knowledge of the anatomy, pharmacology, physiology and pathology of the substantia nigra pars compacta (SNc) dopaminergic neurons. The single chapters, written by top scientists in their fields, explore the life cycle...
Corporate Author: | |
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Other Authors: | , , |
Format: | Electronic |
Language: | English |
Published: |
Vienna :
Springer Vienna,
2009.
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Series: | Journal of Neural Transmission. Supplementa,
73 |
Subjects: | |
Online Access: | https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-3-211-92660-4 |
Table of Contents:
- Preface, G. Di Giovanni, V. Di Matteo, E. Esposito
- Part 1: Birth of Dopaminergic Neurons: Ontogeny of Substantia Nigra Dopamine Neurons
- Part 2: SNc Dopaminergic Neurons: Phenotype, Compartmental Organization and Differential Vulnerability of Nigral Dopaminergic Neurons; Specific Vulnerability of Substantia Nigra Compacta Neurons; The Nigrostriatal Pathway: Axonal Collateralization and Compartmental Specificity; The Localisation of Inhibitory Neurotransmitter Receptors on Dopaminergic Neurons of the Human Substantia Nigra; Basal Ganglia Control of Substantia Nigra Dopaminergic Neurons; Substantia Nigra Control of Basal Ganglia; Electrophysiological Characteristics of Dopamine Neurons: A 35-Year Update; Chaotic Versus Stochastic Dynamics: A Critical Look at the Evidence for Nonlinear Sequence Dependent Structure in Dopamine Neurons; Age-Dependent Changes in Dopaminergic Neuron Firing Patterns in Substantia Nigra Pars Compacta; The Neurobiology of the Substantia Nigra Pars Compacta: from Motor to Sleep Regulation; Non-Motor Function of the Midbrain Dopaminergic Neurons; The Substantia Nigra, the Basal Ganglia, Dopamine and Temporal Processing; Electrophysiological and Neurochemical Characterization of 7-Nitroindazole and Molsidomine Acute and Sub-Chronic Administration Effects in the Dopaminergic Nigrostriatal System in Rats. Part 3: Death of SNc Dopaminergic Neurons: Involvement of Astroglial Fibroblast Growth Factor-2 and Microglia in the Nigral 6-Ohda Parkinsonism and a Possible Role of Glucocorticoid Hormone on the Glial Mediated Local Trophism and Wound Repair; Age and Parkinsons Disease-Related Neuronal Death in the Substantia Nigra Pars Compacta; Neurodegeneration in Parkinsons Disease: Genetics Enlightens Physiopathology; In Vivo Microdialysis in Parkinsons Research; Inflammatory Response in Parkinsonism; Increase of Secondary Processes of Microglial and Astroglial Cells After MPTP-Induced Degeneration in Substantia Nigra Pars Compacta of Non Human Primates; Distinct Effects of Intranigral L-DOPA Infusion in the MPTP Rat Model of Parkinsons Disease; Cannabinoid CB1 Receptors are Early Down-Regulated Followed by a Further Up-Regulation in the Basal Ganglia of Mice with Deletion of Specific Park Genes
- Part 4: Saving the SNc Dopaminergic Neurons: Neurogenesis in Substantia Nigra of Parkinsonian Brains?; Stem Cells And Cell Replacement Therapy For Parkinsons Disease; Gene Therapy for Parkinsons Disease; Immunization as Treatment for Parkinsons Disease; A Diet for the Dopaminergic Neurons?; Intake of Tomato-Enriched Diet Protects from 6-Hydroxydopamine-Induced Degeneration of Rat Nigral Dopaminergic Neurons.