Sequence Comparison Theory and Methods /

• Main Authors: Chao, Kun-Mao. (Author), Zhang, Louxin. (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic
• Language: English
• Published: London : Springer London, 2009.
• Series: Computational Biology, 7
• Subjects: Computer science.; Computer software.; Computer vision.; Bioinformatics.; Computer Science.; Computational Biology/Bioinformatics.; Computer Imaging, Vision, Pattern Recognition and Graphics.; Algorithm Analysis and Problem Complexity.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-84800-320-0

Biomolecular sequence comparison is the origin of bioinformatics. Today, powerful sequence comparison methods, together with comprehensive biological databases, have changed the practice of molecular biology and genomics. This in-depth, state-of-the-art study of sequence alignment and homology searc...

Table of Contents:

• Introduction
• Part I: Algorithms and Techniques
• Basic Algorithmic Techniques
• Pairwise Sequence Alignment
• Homology Search Tools
• Multiple Sequence Alignment
• Part II: Theory
• Anatomy of Spaced Seeds
• Local Alignment Statistics
• Scoring Matrices
• A: Basic Concepts in Molecular Biology
• B: Elementary Probability Theory
• C: Software Packages for Sequence Alignment
• Index.