Computing for Comparative Microbial Genomics Bioinformatics for Microbiologists /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Ussery, David W. (Editor), Wassenaar, Trudy M. (Editor), Borini, Stefano. (Editor)
• Format: Electronic
• Language: English
• Published: London : Springer London, 2009.
• Series: Computational Biology, 8
• Subjects: Computer science.; Human genetics.; Electronic data processing.; Bioinformatics.; Computer Science.; Computational Biology/Bioinformatics.; Computing Methodologies.; Human Genetics.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-84800-255-5

The major difficulty many microbiologists face is simply that of too much information. As a result of sequencing technologies becoming so economical, there is a very real and pressing need for high-throughput computational methods to compare hundreds and thousands of bacterial genomes. This accessib...

Table of Contents:

• Part I: Introductions
• Sequences as Biological Information: Cells Obey the Laws of Chemistry and Physics
• Bioinformatics for Microbiologists
• Microbial Genome Sequences: A New Era in Microbiology
• An Overview of Genome Databases
• The Challenges of Programming: A Brief Introduction- Part II: Comparative Genomics
• Methods to Compare Genomes: The First Examples
• Genome Length and DNA Base Composition
• Word Frequencies, Repeats and Repeat-related Structures
• Part III: Transcriptomics and Proteomics
• Transcriptomics: Translated and Untranslated RNA
• Expression of Genes and Proteins
• Of Proteins, Genomes and Proteomes
• Part IV: Microbial Communities
• Microbial Communities: Core and Pan-genomics
• Metagenomics of Microbial Communities
• Evolution of Microbial Communities.