Stem Cells and Cancer

Significance of Stem Cells to Tumor Development Cancer stem cells remain a controversial topic and the criteria that define cancer stem cells are continuing to evolve. A recent surge in stem cell research has ignited a field of discovery into many human diseases including diabetes, neuropathologies,...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Teicher, Beverly A. (Editor), Bagley, Rebecca G. (Editor)
Format: Electronic
Language:English
Published: Totowa, NJ : Humana Press, 2009.
Series:Cancer Drug Discovery and Development
Subjects:
Online Access:https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-60327-933-8
Table of Contents:
  • Introduction To Cancer Stem Cells. The Cancer Stem Cell Hypothesis. Tumor Stem Cells and Malignant Cells, One and the Same
  • The Stem Cell Niche. Mesenchymal Stem Cells in Tumor Stroma
  • Molecular Pathways And Gene Expression. Wnt Signaling in Cancer: from Embryogenesis to Stem Cell Self-Renewal. PTEN in Hematopoietic and Intestinal Stem Cells and Cancer. Transcription Factors in Cancer Stem Cells of the Hematopoietic Lineage. Stem Cell Chromatin Patterns and DNA Hypermethylation. Plasticity Underlying Multipotent Tumor Stem Cells
  • Cancer Stem Cells In Solid Tumors. Glioma Stem Cells in the Context of Oncogenesis. Mouse Mammary Tumor Virus: Stem Cells and Mammary Cancer. Tumor Dormancy, Metastasis, and Cancer Stem Cells. Cancer Stem Cells  Gastrointestinal Cancers. Cancer Stem Cells  Hepatocellular Carcinoma. Cancer Stem Cells - Lung Cancer. Cancer Stem Cells  Pancreatic Cancer.-Prostate Stem Cells and Cancer in Animals. Prostate Cancer Stem/Progenitor Cells. Adult Prostate Epithelium Renewal, Stem Cells and Cancer. Stem Cells, Angiogenesis and Neurogenesis in Tumors.-Targeting Cancer Stem Cells With Therapy. Implications of Cancer Stem Cells in for Cancer Therapy. Targeting Leukemic Stem Cells. Targeting Brain Cancer Stem Cells in the Clinic. Critical Roles of Tumorigenic and Migrating Cancer Stem/Progenitor Cells in Cancer Progression and their Therapeutic Implications. Therapeutic Index and the Cancer Stem Cell Paradigm.