Functional Selectivity of G Protein-Coupled Receptor Ligands New Opportunities for Drug Discovery /
Functional selectivity refers to the ability of different ligands acting at one receptor subtype to activate multiple signaling pathways in unique combinations; that is, one drug can be an agonist at pathway A and an antagonist or partial agonist at pathway B, and another drug can have the reverse p...
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Format: | Electronic |
Language: | English |
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Totowa, NJ :
Humana Press,
2009.
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Series: | The Receptors
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Online Access: | https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-60327-335-0 |