Functional Selectivity of G Protein-Coupled Receptor Ligands New Opportunities for Drug Discovery /

Functional selectivity refers to the ability of different ligands acting at one receptor subtype to activate multiple signaling pathways in unique combinations; that is, one drug can be an agonist at pathway A and an antagonist or partial agonist at pathway B, and another drug can have the reverse p...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Neve, Kim A. (Editor)
Format: Electronic
Language:English
Published: Totowa, NJ : Humana Press, 2009.
Series:The Receptors
Subjects:
Online Access:https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-60327-335-0