From Local Invasion to Metastatic Cancer Involvement of Distant Sites Through the Lymphovascular System /
In human solid tumors, nodal status is the most important prognostic indicator for patient outcome. Recent developments in the sentinel lymph node concept have resulted in new procedures to define the first draining node as the primary gateway through which the cancer will spread. In From Local Inva...
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Format: | Electronic |
Language: | English |
Published: |
Totowa, NJ :
Humana Press : Imprint: Humana Press,
2009.
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Series: | Current Clinical Oncology
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Online Access: | https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-60327-087-8 |
Table of Contents:
- Introduction
- Dynamic Reciprocity Between Tumor Cells and the Microenvironment
- Inflammation as a Regulator of Epithelial Cancer Development
- Targeting Molecular Signals in the Tumor Cell Microenvironment
- Convergence of Embryonic and Tumorigenic Pathways: Role in Tumor Progression
- Heme-Lymph Vasculo/Angiogenesis, Angiotumorigenesis, and Tumor Angiogenesis: A Lymphatic System Perspective
- Model Systems to Study Lymphangiogenesis and Angiogenesis: Lessons for Tumor Biology
- Vascular Permeability Factor, Lymphangiogenesis/Angiogenesis, and Cancer Biology
- Molecular Events and Clinical Correlations in Tumor and Other Lymphangiogenesis
- Tumor Lymphangiogenesis: What We Know and Don't Know
- Molecular Imaging of Cancer - Receptors, Angiogenesis and Gene Expression
- MRI and Ultrasound Imaging of Lymph Node
- Molecular Imaging of the Sentinel Lymph Node
- Lymphatic Dysfunction and Scintigraphy in Cancer Patients
- Molecular Imaging of Neuroendocrine Cancer by fusion SPECT/CT
- Concepts and Tools of Imaging Cancer
- Therapeutic Targeting of the Lymphovascular System
- Targeted Introduction of Substances into the Lymph Nodes for Endolymphatic Therapy
- Targeting Lymphovascular Endothelium with Anti-VEGFR-3 Monoclonal Antibodies
- Radioimmunotherapy for Cancer
- Animal Models to Study Lymphatic and Vascular Metastasis
- Early Development of Micrometastasis in Tumor-Draining Regional Lymph Nodes: Can They Be Predicted
- Micrometastasis in Patients with Solid Epithelial Tumors
- Imaging Tumor Metastasis and Dormancy in Experimental Models
- Chemokine Receptors and Organ-Specific Metastasis
- Tumor and Lymph Node Lymphangiogenesis: Impact on Metastasis
- Role of the Tumor Microenvironment on Tumor Cell Survival and Metastasis
- Treg, Chemokines and other Small Molecules: Role in Metastasis and its Prevention
- Breast Cancer Metastasis to the Brain
- Chemokines, Lymphatics and Metastasis
- Molecular Targeting of Lymphangiogenesis and Tumor Metastasis
- Beyond VEGF: Angiopoietins and Ephrins as Therapeutic Targets
- VEGF Trap in Trials Today, and VelociGene with VelocImmune for the Angiogenesis Targets of Tomorrow
- Targeting EGFR/Angiogenesis
- Targeting Signaling Pathways in Cancer Therapy
- Micrometastasis of Melanoma to SLNs.-Micrometastasis of Breast Cancer to SLNs
- Micrometastasis of Head and Neck Cancer to SLNs
- Micrometastasis of Genitounrinary Cancer to SLNs
- Micrometastasis of Colorectal Cancer to SLNs
- Micrometastasis of Upper GI Cancer to SLNs
- Application of Cancer Biology in Cancer Staging and Predicting Clinical Outcome.-Should Regional Lymph Node Dissection be done for Breast Cancer?
- Role of Lymph Nodes in Immunotherapy of Malignant Tumors
- Tumor-Related Immune Modulation of the Regional Lymph Nodes
- Reversal of Immune Suppression in Sentinel Lymph Nodes
- Immunomodulation of the Sentinel Node and Systemic Immunity in Melanoma
- Vaccine-Primed Lymph Node Cells in the Adoptive Immunotherapy of Cancer
- Laboratory Monitoring of Immune Functions in Immunotherapy Trials
- Strategies of Developing Cancer Immunotherapies
- Stem Cells in Metastatic Melanoma
- Implications of Cancer Stem Cells for Metastasis
- Prostate Cancer Stem Cells: Identification, Characterization, Regulation of Self Renewal, and Involvement in Metastasis
- Molecular Tecniques to Study Gene Profiles of Cancer
- Gene Signatures and Profiling in Cancer
- Molecular Subgrouping of Breast Cancer Patients
- Molecular Subgrouping of Colon Cancer Patients
- Validating Gene Expression Signatures in Melanoma
- Targeted Therapy for Breast Cancer
- Signifigance of Circulating Tumor Cells in Breast Cancer and other Solid Tumors
- Advances in the Treatment of Colorectal Cancer: Targeting Receptors and Sites of Disease
- Advances in the Treatment of Genitourinary Cancers
- Advances in the Treatment of Lung Cancer
- Genomic Characterization of Malignant Melanoma
- Pegylated Interferons in the Adjuvant Treatment of Melanoma
- Sorafenib, a Multi-kinase Inhibitor, in Metastatic Melanoma
- Breaking Immune Tolerance: a Step Forward in Melanoma Treatment
- Cutaneous Metastases: New Treatment Options
- Neoadjuvant Approaches in Melanoma
- Chemo-/Biochemotherapy: Old Fashioned or Still a Standard of Care?
- Diagnosis and Intervention of Cancer: Vision of the National Cancer Institute
- The Pathogenesis of Organ-Tissue Specific Metastasis
- Lymphatic Mapping and Sentinel Lymphadenectomy: A Personal Journey
- Vascular Endothelial Growth Factor Family, Cancer Biology and Treatment: From Bench to Bedside
- Proliferation and Cancer Metastasis from the Clinical Point of View
- Future Perspectives.