The Cannabinoid Receptors

• Corporate Author: SpringerLink (Online service)
• Other Authors: Reggio, Patricia H. (Editor)
• Format: Electronic
• Language: English
• Published: Totowa, NJ : Humana Press, 2009.
• Series: The Receptors
• Subjects: Medicine.; Neurosciences.; Toxicology.; Cell receptors.; Neurobiology.; Biomedicine.; Pharmacology/Toxicology.; Receptors.; Molecular Medicine.
• Online Access: https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-59745-503-9

As research has progressed, the cannabinoid CB 1 and CB 2 receptors have expanded significantly in importance within the neuroscience mainstream. In The Cannabinoid Receptors, leading experts introduce newcomers to the cannabinoid field with chapters covering cannabinoid ligand synthesis and structu...

Table of Contents:

• Structure Activity Relationships (SAR) of Classical Cannabinoids
• Endocannabinoids and Their Synthetic Analogs
• Cannabimimetic Indoles, Pyrroles and Indenes: Structure-Activity Relationships and Receptor Interactions
• Structure-Activity Relationships and Conformational Freedom of CB1 Receptor Antagonists and Inverse Agonists
• Cannabinoid Receptor Genetics and Evolution
• Cannabinoid Receptor Signal Transduction Pathways
• Cannabinoid Agonist and Inverse Agonist Regulation of G-Protein Coupling
• Molecular Biology of Cannabinoid Receptors: Mutational Analyses of the CB Receptors
• Models of Cannabinoid Inverse Agonism, Neutral Antagonism and Agonism: Tools for Rational Drug Design
• Endocannabinoids as Modulators of Synaptic Signaling
• New Insights into the Endocannabinoid System by using Cannabinoid Receptor Knockout Mice
• Preclinical Pharmacological and Brain Bioassay Systems for CB1 Cannabinoid Receptors
• Therapeutic Applications for Agents that Act at CB1 and CB2 Receptors.