Cover Image

Molecular Mechanisms of Spondyloarthropathies

It is now over ten years since we edited the first edition of HLA-B27 in the Development of Spondyloarthropathies (SpA). It is obvious that over this period an enormous amount of information concerning SpA and HLA-B27 has accumulated, and this has been reflected in the knowledge of molecular mechani...

Full description

Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Lp̤ez-Larrea, Carlos. (Editor), Da̕z-Peą, Roberto. (Editor)
Format: Electronic
Language:English
Published: New York, NY : Springer New York : Imprint: Springer, 2009.
Series:Advances in Experimental Medicine and Biology, 649
Subjects:
Medicine.
Biomedicine.
Biomedicine general.
Online Access:https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-4419-0298-6
Table of Contents:
  • 1. Clinical Assessment in the Spondyloarthropathies
  • 2. Imaging in Spondyloarthritis
  • 3. Spondyloarthritis, Diffuse Idiopathic Skeletal Hyperostosis (DISH) and Chondrocalcinosis
  • 4. The Enthesis Organ Concept and its Relevance to the Spondyloarthropathies
  • 5. Synovial and Mucosal Imunopathology in Spondyloarthritis
  • 6. Bone Loss in the Spondyloarthropathies: Role of Osteoclast, Rankl, Rank and Opg in the Spondyloarthropathies
  • 7. RankL/Rank as Key Factors for Osteoclast Development and Bone Loss in Arthropathies
  • 8. Bone Formation Versus Bone Resorption in Ankylosing Spondylitis
  • 9. Biomarkers in Spondyloarthropathies
  • 10. Therapy of Spondyloarthritides
  • 11. Genomewide Screens in Ankylosing Spondylitis
  • 12. Subtypes of HLA-B27: History and Implications in the Pa thogenesis of Ankylosing Spondylitis
  • 13. Implications of Structural and Thermodynamic Studies of Hla-B27 Subtypes Exhibiting Differential Association with Ankylosing Spondylitis
  • 14. HLA-B27-Bound Peptide Repertoires: Their Nature, Origin and Pa thogenetic Relevance
  • 15. Biochemical Features of Hla-B27 and Antigen Processing
  • 16. HLA-B27 Misfolding and Spondyloarthropathies
  • 17. HLA-B27 and Host-Pa thogen Interaction
  • 18. Animal Models of Spondyloarthritis
  • 19. T-Cell Responses Against Viral and Self-Epitopes and Hla-B27 Subtypes Differentially Associated with Ankylosing Spondylitis
  • 20. Dendritic Cell: T-Cell Interactions in Spondyloarthritis
  • 21. The Role of B27 Heavy Chain Dimer Imune Receptor Interactions in Spondyloarthritis
  • 22. KIR Genes and Their Role in Spondyloarthropathies
  • 23. Innate Imunity of Spondyloarthritis: The Role of Toll-Like Receptors.

Similar Items