Viral Genome Replication

Currently, there is no single source that permits comparison of the factors, elements, enzymes and/or mechanisms employed by different classes of viruses for genome replication. As a result, we (and our students) often restrict our focus to our particular system, missing out on the opportunity to de...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Raney, Kevin D. (Editor), Gotte, Matthias. (Editor), Cameron, Craig E. (Editor)
Format: Electronic
Language:English
Published: Boston, MA : Springer US, 2009.
Subjects:
Online Access:https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/b135974
Table of Contents:
  • Genome replication strategies
  • plus-strand RNA viruses
  • Model of Picornavirus RNA Replication
  • Coronavirus Genome Replication
  • Flaviviruses
  • Hepatitis C virus genome replication
  • Brome mosaic virus RNA replication and transcription
  • Retroviruses
  • Hepadnaviral genomic replication
  • minus-strand RNA viruses
  • Orthomyxoviruses genome transcription and replication
  • ambisense RNA viruses
  • Arenaviruses: Genome replication strategies
  • dsRNA viruses
  • Core-associated genome replication mechanisms of dsRNA viruses
  • DNA viruses
  • Poxviruses
  • Herpesevirus genome replication
  • Host factors
  • Host factors promoting replication
  • Host factors that restrict retrovirus replication
  • Elements, factors and enzymes: Structure-function and mechanism
  • T4 Phage Replisome
  • Atomic structure of the Herpes Simplex Virus 1 DNA polymerase
  • RNA virus polymerases
  • Human immunodeficiency virus reverse transcriptase
  • Viral helicases
  • Integrase: structure, function and mechanism
  • Antivirals: Targets, mechanisms and resistance
  • Viral DNA polymerase inhibitors
  • RNA polymerase inhibitors
  • HIV reverse transcriptase inhibitors and mechanisms of resistance
  • Lethal mutagenesis
  • Clinical implications of reverse transcriptase inhibitor resistance.