Cardiac Bioelectric Therapy Mechanisms and Practical Implications /

Pacing and defibrillation have become the leading therapeutic treatments of heart rhythm disorders, including bradycardia and tachycardia. The history of the successful development of bioelectric therapies includes the development of experimental and theoretical methodologies, novel bioengineering a...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Efimov, Igor R. (Editor), Kroll, Mark W. (Editor), Tchou, Patrick J. (Editor)
Format: Electronic
Language:English
Published: Boston, MA : Springer US, 2009.
Subjects:
Online Access:https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-0-387-79403-7
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505 0 # |a History of Cardiac Pacing -- History of Defibrillation -- Ventricular Fibrillation: A Historical Perspecitve -- The Bidomain Theory of Pacing -- Bidomain Model of Defibrillation -- The Generalized Activating Function -- Theory of Electroporation -- Critical Points and the ULV for Defibrillation -- The Role of Shock-induced Non-regenerative Depolarization inVentricular Fibrillation and Defibrillation: The Graded Response Hypothesis -- Mechanisms of Isolated Cell Stimulation -- The Role of Microscopic Tissue Structure in Defibrillation -- Virtual Electrode Theory of Pacing -- The Virutal Electrode Hypothesis of Defibrillation -- Simultaneous Optical and Electrical Recordings -- Optical Mapping of Multi-site VF Synchronization -- The Bidomain Model of Cardiac Tissue: From Microscale to Macroscale -- Multi-electrode Mapping ofthe Heart -- The Role of Electroporation -- Lessons for the Clinical Implant -- Resonance and Feedback Strategies for Low-voltage Defibrillation -- Pacing Control of Local Cardiac Dynamics -- Advanced Methods for Assessing the Stability and Control of Alternans -- The Future of the Implantable Defibrillator -- Lessons Learned from ICD Recordings -- Index. 
520 # # |a Pacing and defibrillation have become the leading therapeutic treatments of heart rhythm disorders, including bradycardia and tachycardia. The history of the successful development of bioelectric therapies includes the development of experimental and theoretical methodologies, novel bioengineering approaches and state-of-the-art clinical implantable device therapies. This volume will present a uniform thematic collection of reviews written by the leading basic and applied scientists working in basic bioengineering research laboratories, who have contributed to the development of current understanding of the fundamental mechanisms of pacing and electrophysiology, and who are at the leading edge of further developments in electrotherapy. Igor R. Efimov, Ph.D., is Associate Professor of Biomedical Engineering, Washington University, St. Louis, Missouri. Mark W. Kroll, Ph.D., is Adjunct Professor Biomedical Engineering, California Polytechnic University and University of Minnesota.. Patrick J. Tchou, M.D. is in the Section of Cardiac Electrophysiology and Pacing at the Cleveland Clinic in Cleveland, Ohio. 
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