From protein structure to function with bioinformatics /

• Other Authors: Rigden, Daniel John, (Editor)
• Format: eBook
• Language: English
• Published: The Netherlands : Springer, [2017]
• Edition: Second edition.
• Subjects: Proteins > Structure-activity relationships > Research > Methodology.; Proteins > Structure > Research > Methodology.; Proteins > Structure.; Proteins > Structure > Computer simulation.; Bioinformatics.; SCIENCE > Life Sciences > Biochemistry.; Electronic books.
• Online Access: View fulltext via EzAccess

This book is about protein structural bioinformatics and how it can help understand and predict protein function. It covers structure-based methods that can assign and explain protein function based on overall folds, characteristics of protein surfaces, occurrence of small 3D motifs, protein-protein...

Table of Contents:

• Preface
• Ab Initio Protein Structure Prediction
• Protein structures, interactions and function from evolutionary couplings.-Fold Recognition
• Comparative protein structure modelling
• Advances in computational methods for transmembrane protein structure prediction
• Bioinformatics approaches to the structure and function of intrinsically disordered proteins
• Prediction of Protein Aggregation and Amyloid Formation
• Prediction of biomolecular complexes
• Function Diversity within Folds and Superfamilies
• Function prediction using patches, pockets and other surface properties
• 3D Motifs
• Protein Dynamics: From Structure to Function
• Integrated servers for structure-informed function prediction
• Case Studies: Function Predictions Of Structural Genomics Results
• Prediction of protein function from theoretical models
• Index.