Tremor from pathogenesis to treatment /

Tremor represents one of the most common movement disorders worldwide. It affects both sexes and may occur at any age. In most cases, tremor is disabling and causes social difficulties, resulting in poorer quality of life. Tremor is now recognized as a public health issue given the ageing of the pop...

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Bibliographic Details
Main Author: Grimaldi, Giuliana.
Other Authors: Manto, Mario-Ubaldo.
Format: Electronic
Language:English
Published: San Rafael, Calif. (1537 Fourth St, San Rafael, CA 94901 USA) : Morgan & Claypool Publishers, c2008.
Series:Synthesis lectures on biomedical engineering, #20.
Subjects:
Online Access:Abstract with links to resource
Table of Contents:
  • Introduction
  • Definition of tremor
  • Physiological tremor
  • Sources of tremor : neuronal networks
  • Cerebral cortex
  • Basal ganglia and thalamus
  • Cerebellum
  • Spinal cord
  • Peripheral nerves
  • Neuromuscular junction
  • Muscle
  • Muscle spindles and other peripheral receptors
  • Physiology of the nervous system
  • Membrane potential : basic concepts
  • The synapses
  • Excitatory and inhibitory synapses : neurotransmitters and their receptors
  • Integrative action of the nervous system
  • Structures involved in information processing and movement control
  • Characterization of tremor
  • Physiological tremor and enhanced physiological tremor
  • Rest tremor
  • Postural tremor
  • Kinetic tremor
  • Action tremor
  • Other forms of tremor
  • Principal disorders associated with tremor
  • Essential tremor
  • Idiopathic Parkinson's disease
  • Cerebellar diseases
  • Miscellaneous
  • Role of brain imaging in the differential diagnosis of tremor
  • Quantification of tremor
  • Clinical examination and clinical scales
  • Electromyography and motor unit studies
  • Kinematic studies
  • Haptic devices
  • Signal processing
  • Mechanisms of tremor
  • Blood studies
  • Brain imaging
  • Contribution of animal models in the identification of the cause of tremor
  • Physiological tremor
  • Enhanced physiological tremor
  • Postural tremor and essential tremor
  • Rest tremor and Parkinson's disease
  • Kinetic tremor
  • Orthostatic tremor
  • Other tremors
  • Treatments
  • Drugs
  • Deep brain stimulation and surgical treatments
  • Gamma knife
  • Transcranial magnetic stimulation
  • Orthosis and prosthesis
  • Brain-machine interfaces
  • Assistive therapy
  • Fuzzy logics.