Biological data mining in protein interaction networks

• Corporate Author: IGI Global.
• Other Authors: Li, Xiao-Li, 1969-, Ng, See-Kiong.
• Format: Electronic
• Language: English
• Published: Hershey, Pa. : IGI Global (701 E. Chocolate Avenue, Hershey, Pennsylvania, 17033, USA), c2009.
• Subjects: Protein-protein interactions > Data processing.; Proteomics.; Data mining.; Protein Interaction Mapping > methods.; Computational Biology > methods.; Databases, Protein.; Data mining for biologists; Discovering interaction motifs; Discovering lethal proteins; Discovering protein complexes; Molecular biology of protein-protein interactions; Network motifs in protein interaction networks; Predicting protein functions; Predicting protein-protein interactions; Prioritizing disease genes; Protein interaction networks; Reliable protein interaction networks
• Online Access: View fulltext via EzAccess

"The goal of this book is to disseminate research results and best practices from cross-disciplinary researchers and practitioners interested in, and working on bioinformatics, data mining, and proteomics"--Provided by publisher.

Table of Contents:

• Section 1. Introduction
• 1. Molecular biology of protein-protein interactions for computer scientists / Christian Schönbach
• 2. Data mining for biologists / Koji Tsuda
• Section 2. PPI Network Construction and Cleansing
• 3. Domain-based prediction and analysis of protein interaction networks / Tatsuya Akutsu, Morihiro Hayashida
• 4. Incorporating graph features for predicting protein-protein interactions / Martin Samuel Rao Paradesi, William H. Hsu, Doina Caragea
• 5. Discovering protein-protein interaction sites from sequence and structure / David La, Daisuke Kihara
• 6. Network cleansing : reliable protein interaction networks / Paolo Marcatili, Anna Tramontano
• Section 3. Knowledge Discovery from PPI Networks
• 7. Discovering interaction motifs from protein interaction networks / Willy Hugo
• 8. Discovering network motifs in protein interaction networks / Raymond Wan, Hiroshi Mamitsuka
• 9. Discovering protein complexes in protein interaction networks / Clara Pizzuti, Simona Ester Rombo
• 10. Evolutionary analyses of protein interaction networks / Takashi Makino, Aoife McLysaght
• Section 4. Biological Applications Using PPI Analysis
• 11. Discovering lethal proteins in protein interaction networks / Kar Leong Tew, Xiao-Li Li
• 12. Predicting protein functions from protein interaction networks / Hon Nian Chua, Limsoon Wong
• 13. Protein interactions for functional genomics / Pablo Minguez, Joaquin Dopazo
• 14. Prioritizing disease genes and understanding disease pathways / Xiaoyue Zhao, Lilia M. Iakoucheva, Michael Q. Zhang
• 15. Dynamics of protein-protein interaction network in plasmodium falciparum / Smita Mohanty, Shashi Bhushan Pandit, Narayanaswamy Srinivasan
• Section 5. Tools for Analysis of PPI Networks
• 16. Graphical analysis and visualization tools for protein interaction networks / Sirisha Gollapudi ... [et al.]
• 17. Network querying techniques for PPI network comparison / Valeria Fionda, Luigi Palopoli
• 18. Module finding approaches for protein interaction networks / Tero Aittokallio
• Compilation of References
• About the Contributors
• Index.