Introduction to neuroglia /

This book is the introduction to a series of e-books dedicated to physiology and pathophysiology of neuroglia. The topic of neuroglia is generally overlooked in neuroscience curricula across the world, the main attention being focused on the description of excitability of neurons and neuronal networ...

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Bibliographic Details
Main Authors: Verkhratskiĭ, A. N. (Author), Parpura, Vladimir, 1964- (Author)
Format: eBook
Language:English
Published: San Rafael, California (1537 Fourth Street, San Rafael, CA 94901 USA) : Morgan & Claypool, 2014.
Series:Colloquium Digital Library of Life Sciences.
Colloquium series on neuroglia in biology and medicine ; # 1.
Subjects:
Online Access:View fulltext via EzAccess
Table of Contents:
  • 1. Introduction
  • 1.1 General perspective
  • 1.2 History of neuroscience and emergence of neuroglia
  • 1.2.1 Neuroscience in antiquity
  • 1.2.2 Cortical localization of brain functions
  • 1.2.3 The cellular theory and discovery of neural cells
  • 1.2.4 The concept of neuroglia
  • 2. Definition, classification, and evolution of neuroglia
  • 2.1 Definition of neuroglia
  • 2.2 Classification of neuroglia
  • 2.3 Evolution of neuroglia
  • 2.3.1 Parenchymal homeostasis-maintaining glia, i.e., astroglia
  • 2.3.2 Evolution of myelination
  • 2.3.3 Evolution of microglia
  • 2.4 Numbers: how many glial cells are in the brain?
  • 3. Functions of neuroglia
  • 3.1 Astroglia
  • 3.1.1 Control of nervous system development
  • 3.1.2 Adult neurogenesis and gliogenesis
  • 3.1.3 Micro-architecture of the grey matter
  • 3.1.4 Formation of the blood-brain barrier
  • 3.1.5 Regulation of microcirculation
  • 3.1.6 Metabolic homeostasis
  • 3.1.7 Water homeostasis
  • 3.1.8 Dynamic regulation of extracellular volume
  • 3.1.9 Osmotic homeostasis
  • 3.1.10 Ion homeostasis
  • 3.1.11 pH homeostasis
  • 3.1.12 Neurotransmitter homeostasis
  • 3.1.13 Reactive oxygen species homeostasis
  • 3.1.14 Central chemoception
  • 3.1.15 Release of neurotransmitters and neuromodulators
  • 3.1.16 Regulation of synaptic transmission
  • 3.1.17 Circadian rhythms
  • 3.1.18 Sleep
  • 3.1.19 Female sexual maturity
  • 3.1.20 Light guidance
  • 3.1.21 Defensive role: reactive astrogliosis
  • 3.2 Oligodendroglia
  • 3.3 NG2 cells
  • 3.4 Microglia
  • 3.4.1 Origin
  • 3.4.2 Physiological functions of microglia
  • 3.4.3 Defensive function: innate immunity and phagocytosis
  • 3.5 Peripheral glia
  • Concluding remarks
  • References
  • Author biographies.