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Challenges and Opportunities for Respiratory Syncytial Virus Vaccines

Although respiratory syncytial virus (RSV) has been a high priority for vaccine development for over 50 years now, still no vaccine is available and none has yet demonstrated sufficient promise to move to licensure. The success of RSV immune prophylaxis and the availability of ever more powerful too...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Anderson, Larry J. (Editor), Graham, Barney S. (Editor)
Format: Electronic
Language:English
Published: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer, 2013.
Series:Current Topics in Microbiology and Immunology, 372
Subjects:
Medicine.
Vaccines.
Virology.
Infectious diseases.
Respiratory organs > Diseases.
Pediatrics.
Biomedicine.
Vaccine.
Infectious Diseases.
Pneumology/Respiratory System.
Online Access:View fulltext via EzAccess
Table of Contents:
  • Respiratory Syncytial Virus: Virology, Reverse Genetics, and Pathogenesis of Disease
  • Clinical and Epidemiologic Features of Respiratory Syncytial Virus
  • Influence of Respiratory Syncytial Virus Strain Differences on Pathogenesis and Immunity
  • Structure and Function of Respiratory Syncytial Virus Surface Glycoproteins
  • Respiratory Syncytial Virus and Reactive Airway Disease
  • Human Genetics and Respiratory Syncytial Virus Disease: Current Findings and Future Approaches
  • Innate Immune Responses to Respiratory Syncytial Virus Infection
  • The Adaptive Immune Response to Respiratory Syncytial Virus
  • Respiratory Syncytial Virus Mechanisms to Interfere with Type 1 Interferons
  • Host Gene Expression and Respiratory Syncytial Virus Infection
  • Consequences of Immature and Senescent Immune Responses for Infection with Respiratory Syncytial Virus
  • Respiratory Syncytial Virus Disease:  Prevention and Treatment
  • Live-Attenuated Respiratory Syncytial Virus Vaccines
  • Subunit and Virus-Like Particle Vaccine Approaches for Respiratory Syncytial Virus
  • Gene-Based Vaccine Approaches for Respiratory Syncytial Virus
  • Bovine Model of Respiratory Syncytial Virus Infection
  • The Cotton Rat S. hispidus Model of Respiratory Syncytial Virus Infection
  • The Mouse Model of Respiratory Syncytial Virus Disease
  • Human Airway Epithelial Cell Cultures for Modeling Respiratory Syncytial Virus Infection
  • Challenges and Opportunities for Respiratory Syncytial Virus Vaccines.

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