E-Cell System Basic Concepts and Applications /

The interdisciplinary field of molecular systems biology aims to understand the behavior and mechanisms of biological processes composed of individual molecular components. As we gain more qualitative and quantitative information of complex intracellular processes, biochemical modeling and simulatio...

Full description

Bibliographic Details
Main Authors: Arjunan, Satya Nanda Vel. (Author), Dhar, Pawan K. (Author), Tomita, Masaru. (Author)
Corporate Author: SpringerLink (Online service)
Format: Electronic
Language:English
Published: New York, NY : Springer New York : Imprint: Springer, 2013.
Series:Molecular Biology Intelligence Unit,
Subjects:
Online Access:View fulltext via EzAccess
LEADER 03898nam a22004935i 4500
001 23918
003 DE-He213
005 20151125191920.0
007 cr nn 008mamaa
008 150519s2013 xxu| s |||| 0|eng d
020 # # |a 9781461461579  |9 978-1-4614-6157-9 
024 7 # |a 10.1007/978-1-4614-6157-9  |2 doi 
050 # 4 |a QH506 
072 # 7 |a MBGR  |2 bicssc 
072 # 7 |a PSD  |2 bicssc 
072 # 7 |a SCI049000  |2 bisacsh 
072 # 7 |a MED067000  |2 bisacsh 
082 0 4 |a 611.01816  |2 23 
100 1 # |a Arjunan, Satya Nanda Vel.  |e author. 
245 1 0 |a E-Cell System  |b Basic Concepts and Applications /  |c by Satya Nanda Vel Arjunan, Pawan K. Dhar, Masaru Tomita.  |h [electronic resource] : 
264 # 1 |a New York, NY :  |b Springer New York :  |b Imprint: Springer,  |c 2013. 
300 # # |a 179 p.  |b online resource. 
336 # # |a text  |b txt  |2 rdacontent 
337 # # |a computer  |b c  |2 rdamedia 
338 # # |a online resource  |b cr  |2 rdacarrier 
347 # # |a text file  |b PDF  |2 rda 
490 1 # |a Molecular Biology Intelligence Unit,  |x 1431-0414 
505 0 # |a Introduction to Whole Cell Modeling -- Foundations of EỚ<U+0018>Cell Simulation Environment Architecture -- Distributed Cell Biology Simulations with the EỚ<U+0018>Cell System -- A Guide to Modeling ReactionỚ<U+0018>Diffusion of Molecules with the EỚ<U+0018>Cell System -- A Model Library of Bacterial Chemotaxis on EỚ<U+0018>Cell System -- Electrophysiological Simulation of Developmental Changes in Action Potentials of Cardiomyocytes -- Simulation of Human Erythrocyte Metabolism -- Dynamic Kinetic Modeling of Mitochondrial Energy Metabolism -- A Computational Model of the Hepatic Lobule -- Decoding the Signaling Mechanism of TollỚ<U+0018>Like Receptor 4 Pathways in Wild Type and Knockouts -- Modeling of Hsp70Ớ<U+0018>Mediated Protein Refolding. 
520 # # |a The interdisciplinary field of molecular systems biology aims to understand the behavior and mechanisms of biological processes composed of individual molecular components. As we gain more qualitative and quantitative information of complex intracellular processes, biochemical modeling and simulation become indispensable not only to uncover the molecular mechanisms of the processes, but to perform useful predictions. To this end, the EỚ<U+0018>Cell System, a multiỚ<U+0018>algorithm, multiỚ<U+0018>timescale objectỚ<U+0018>oriented simulation platform, can be used to construct predictive virtual biological systems. Gene regulatory and biochemical networks that constitute a subỚ<U+0018> or a whole cellular system can be constructed using the EỚ<U+0018>Cell System to perform qualitative and quantitative analyses. The purpose of EỚ<U+0018>Cell System: Basic Concepts and Applications is to provide a comprehensive guide for the EỚ<U+0018>Cell System version 3 in terms of the software features and its usage. While the publicly available EỚ<U+0018>Cell Simulation Environment version 3 User's Manual provides the technical details of model building and scripting, it does not describe some of the underlying concepts of the EỚ<U+0018>Cell System. The first part of the book addresses this issue by providing the basic concepts of modeling and simulation with the EỚ<U+0018>Cell System. 
650 # 0 |a Medicine. 
650 # 0 |a Molecular biology. 
650 1 4 |a Biomedicine. 
650 2 4 |a Molecular Medicine. 
650 2 4 |a Biomedicine general. 
700 1 # |a Dhar, Pawan K.  |e author. 
700 1 # |a Tomita, Masaru.  |e author. 
710 2 # |a SpringerLink (Online service) 
773 0 # |t Springer eBooks 
776 0 8 |i Printed edition:  |z 9781461461562 
830 # 0 |a Molecular Biology Intelligence Unit,  |x 1431-0414 
856 4 0 |u https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-1-4614-6157-9  |z View fulltext via EzAccess 
912 # # |a ZDB-2-SBL 
950 # # |a Biomedical and Life Sciences (Springer-11642)