Retinal Degenerative Diseases and Experimental Therapy

• Corporate Author: SpringerLink (Online service)
• Other Authors: Hollyfield, Joe G. (Editor), Anderson, Robert E. (Editor), LaVail, Matthew M. (Editor)
• Format: Electronic
• Language: English
• Published: Boston, MA : Springer US, 1999.
• Subjects: Medicine.; Human genetics.; Pharmacology.; Human anatomy.; Ophthalmology.; Biomedical engineering.; Medicine & Public Health.; Human Genetics.; Biomedical Engineering.; Anatomy.; Pharmacology/Toxicology.
• Online Access: View fulltext via EzAccess

To create a forum for scientists and clinicians interested in degenerative retinal diseases, we began in 1984 to organize a biennial symposium on Retinal Degeneration as a satellite meeting of the International Congress of Eye Research. The timing and varying location of these meetings provides an i...

Table of Contents:

• Specific Gene Defects Cause Photoreceptor Degeneration
• Evidence for Myosin VIIa-Driven Transport of Rhodopsin in the Plasma Membrane of the Photoreceptor-Connecting Cilium
• Blindness in Usher Syndrome 1B
• Different Mutations in RPE65 Are Associated with Variability in the Severity of Retinal Dystrophy
• The RPE65-Deficient Mouse as a Model for RPE65-Associated LeberỚ"s Congenital Amaurosis and Related Disorders
• CRALBP and Inherited Retinal Degeneration
• Guanylyl Cyclase Genes and Their Role in Retinal Degeneration
• Loss of Cone and Reduction in Rod ERG Responses in the Guanylyl Cyclase-E (GC-E) Deficient Mouse
• Guanylyl Cyclase Gene is the Disease Locus in the rd Chicken
• LeberỚ"s Congenital Amaurosis
• Retinal Degeneration is Accelerated when a Mutant Rhodopsin Transgene is Expressed on a Haploid or Null Rhodopsin Background
• Rhodopsin C-Terminal Sequence Qvs(A)Pa Directs Its Sorting To The Ros In Retinal Photoreceptors
• The Cytoplasmic Tail of Rhodopsin Acts as a Sorting Signal in Polarized Photoreceptors and MDCK Cells
• A Homozygous 1-Base Pair Deletion (1147dela) in the Arrestin Gene in Autosomal Recessive Retinitis Pigmentosa
• mRNA Analysis of Oguchi Patients with the Frequent 1147delA Mutation in the Arrestin Gene
• Mutation Spectrum in the Rep-1 Gene of Japanese Choroideremia Patients
• Phenotype-Genotype Correlations in Retinal Degenerations Caused by Abcr gene Mutations
• Autosomal Dominant Macular Degeneration Localized to Chromosome 6q by Linkage Analysis
• The Gene Product of IMPG1 is the Glycoprotein SPACR, not an IPM Proteoglycan
• Bardet-Biedl Syndrome
• Genetic Mapping and Evaluation of PDE6A in 49 Spanish Families with Autosomal Recessive Retinitis Pigmentosa
• Grading Device for Light Perception with Retinitis Pigmentosa
• Blue Cone Monochromacy
• The Peripherin/rds Gene
• Autosomal Dominant Retinitis Pigmentosa and Hyperopia
• Intraocular Pressure in Tapetoretinal Degenerations
• Gene Therapy for Photoreceptor Rescue
• Ribozymes Directed Against Messenger RNAs Associated With Autosomal Dominant Retinitis Pigmentosa
• Ribozyme-Mediated Gene Therapy for Autosomal Dominant Retinal Degeneration
• Targeting M©ơller Cells for Gene Therapy
• The Involvement of Light in Retinal Degeneration
• Dark Adaptation is Impaired in Diabetics before Photopic Visual Losses Can be Seen
• Age and Monocular Enucleation as Potential Determinants of Light Damage in the Mouse Retina
• Ultraviolet Light Damage and Reversal by Retinoic Acid in Juvenile Goldfish Retina
• A Comparison of Light-Induced Rod Degeneration in Two Teleost Models
• Regulation of Light Absorption in the Pigmented Rat Retina
• An Uncoupling Effect of Reactive Oxygen Species on the Retinal Horizontal Cells
• Animal Models with Photoreceptor Degeneration
• Animal Model for Retinitis Pigmentosa
• Development Of Rat Models For Choroidal Neovascularisation (CNV)
• Identification of Degeneration-Specific Genes in the Rcs Rat Retina By Subtractive Hybridization Techniques
• Analysis of Field Potentials and Spike Patterns Evoked by Local Electrical Stimulation of the Chicken Retina
• Molecular and Cell Biological Studies
• Antisense Inactivation of Rds/Peripherin in Xenopus Laevis Embryonic Retinal Cultures
• Phosducin-Like Protein 1 (Phlp1) and Phosducin-Like Orphan Protein 1 (Phlop1)
• Organization of The Interphotoreceptor Matrix
• Diverse Localization of Cyclic Nucleotide Gated Channels in the Outer Segments of Rods and Cones
• Retinal Prosthesis as a Replacement for Photoreceptors
• Development of an Epiretinal Electronic Visual Prosthesis
• Response Characteristics of Subretinal Microphotodiode-Based Implant-Mediated Cortical Potentials
• Electrical Stimulation of the Human Retina
• Goals,Concepts,and Current State of the Retina Implant Project
• Are Subretinal Microphotodiodes Suitable as a Replacement For Degenerated Photoreceptors?
• Neuroprotective Agents Romote Photoreceptor Survival
• Rods Produce a Diffusible Factor Promoting Cone Photoreceptor Survival In Vivo and in Vitro
• Pigment Epithelium-Derived Factor (PEDF) in the Retina
• Retinal Neurons in Primary Cell Culture
• Melatonin Receptor Blockers Enhance Photoreceptor Survival and Function in Light Damaged Rat Retina
• Transplantation Studies
• IRIS Pigment Epithelial Cell Transplantation in Monkey Eyes
• The Retinal Pigment Epithelial Cell Differentiation and Cell Marker Expression Following Cryopreservation at -80℗ʻC and under Liquid Nitrogen at -196℗ʻC.