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Sucralfate From Basic Science to the Bedside /

International researchers summarize the current understanding of peptic disease and trace the development of a novel new drug for peptic disease therapy-sucralfate. Contributors present laboratory research along side data from clinical trials as well as from the practice of medicine. Articles discus...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Hollander, Daniel. (Editor), Tytgat, Guido N. J. (Editor)
Format: Electronic
Language:English
Published: Boston, MA : Springer US, 1995.
Subjects:
Medicine.
Pharmacology.
General practice (Medicine).
Internal medicine.
Gastroenterology.
Hepatology.
Medicine & Public Health.
Internal Medicine.
General Practice / Family Medicine.
Pharmacology/Toxicology.
Online Access:View fulltext via EzAccess
Table of Contents:
  • Pathophysiology of Peptic Ulcer Disease
  • Decreased Intragastric Acid Concentration as an Approach to Peptic Disease Therapy
  • General Approach to Peptic Disease Therapy
  • Ulcer Healing by Strengthening of Mucosal Defense
  • History of the Development of Sucralfate
  • Sucralfate: A Nonsystemic Site Protective Agent
  • Chemistry of Sucralfate
  • Binding of Bile Acids by Sucralfate
  • Mechanisms of Action of Sucralfate
  • Binding of Sucralfate to the Mucosal Surface
  • Stimulation of Mucus Production
  • Gastroduodenal Bicarbonate Secretion and its Response to Sucralfate
  • Effect of Sucrose Octasulfate on Isolated Gastric Cells
  • Effect on Gastric Surfactant
  • Stimulation of Mucosal Prostaglandins by Sucralfate
  • Sucralfate and Helicobacter pylori
  • Sucralfate and Cell Proliferation
  • Vascular Factors
  • Sucralfate
  • Effects of Sucralfate on Growth Factor Availability
  • Duodenal Ulcer Therapy, ỚSAcid Rebound,Ớ<U+00fd> and Early Relapse
  • Effect of Sucralfate on Experimental Ulcers
  • Effect on Experimental Esophageal Injury
  • Safety and Drug Interactions
  • Safety of Sucralfate
  • Sucralfate Drug Interaction Studies
  • Sucralfate and Therapy of Peptic Disease
  • Therapy of Gastric Ulcer Disease
  • Therapy of Active Duodenal Ulcers
  • Prevention of Ulcer Recurrence
  • Therapy of Esophagitis
  • Sucralfate for NSAID-Induced Gastroduodenal Lesions
  • The Preventive Use of Sucralfate
  • Sucralfate for Prevention of Acute Gastrointestinal Bleeding
  • Prevention of Respiratory Tract Infections with Sucralfate in Ventilated ICU Patients
  • Sucralfate in Nonulcer Dyspepsia, Gastritis, and Duodenitis
  • Use of Sucralfate in Variceal Sclerotherapy-Induced Ulcerations
  • The Clinical Role of Sucralfate in Peptic Ulcer TherapyỚ Comparison with H-2 Blockers and Pump Inhibitors: A Projection for the Nineties
  • Future Research into the Mechanisms of Action of Sucralfate
  • Future Clinical Development of Sucralfate.

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