Signal Transduction in Cancer
One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts ha...
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| Format: | Electronic |
| Language: | English |
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Boston, MA :
Springer US,
2003.
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| Series: | Cancer Treatment and Research,
115 |
| Subjects: | |
| Online Access: | View fulltext via EzAccess |
Table of Contents:
- Receptors
- Growth, Survival and Migration: The Trk to Cancer
- The Role of Growth Factor Signaling in Malignancy
- TGF-? Signaling Alterations in Cancer
- Notch in Malignancy
- Intracellular Pathways
- cAMP Signaling in Cancer Genesis and Treatment
- PI3K/PTEN/Akt Pathway
- Wnt Signaling in Human Cancer
- Ras Signaling, Deregulation of Gene Expression and Oncogenesis
- Role of the RB Tumor Suppressor in Cancer
- Transcription Factors
- The Rel/NF-?B/I?B Signal Transduction Pathway and Cancer
- STAT Signaling in Cancer: Insights into Pathogenesis and Treatment Strategies
- Steroid Hormone Receptor Signaling in Cancer
- Cell Death Pathways
- Cell Death Signaling in Malignancy
- Ceramide and Sphingosine 1-Phosphate in Anti-Cancer Therapies.