Data Analysis in Molecular Biology and Evolution

• Main Author: Xia, Xuhua. (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic
• Language: English
• Published: Boston, MA : Springer US, 2002.
• Subjects: Life sciences.; Computer science.; Data structures (Computer science).; Biochemistry.; Evolutionary biology.; Animal anatomy.; Life Sciences.; Animal Anatomy / Morphology / Histology.; Computer Science, general.; Evolutionary Biology.; Data Structures.; Biochemistry, general.
• Online Access: View fulltext via EzAccess

Data Analysis in Molecular Biology and Evolution introduces biologists to DAMBE, a proprietary, user-friendly computer program for molecular data analysis. The unique combination of this book and software will allow biologists not only to understand the rationale behind a variety of computational to...

Table of Contents:

• Installation of DAMBE and a Quick Start
• File Conversion
• Processing GenBank Files
• Accessing GenBank or Other Networked Computers
• Pair-wise and Multiple Sequence Alignment
• Factors Affecting Nucleotide and Di-Nucleotide Frequencies
• Case Study 1
• Factors Affecting Codon Frequencies and Codon Usage Bias
• Case Study 2
• Case Study 3
• Evolution of Amino Acid Usage
• Pattern of Nucleotide Substitutions
• Preamble to the Pattern of Codon Substitution
• Factors Affecting Codon Substitutions
• Case Study 4
• Substitution Pattern in Amino Acid Sequences
• A Statistical Digression
• Theoretical Background of Genetic Distances
• Molecular Phylogenetics: Concepts and Practice
• Testing the Molecular Clock Hypothesis
• Testing Phylogenetic Hypotheses
• Fitting Probability Distributions To Substitutions Over Sites.