Insect Cell Culture: Fundamental and Applied Aspects
| Corporate Author: | |
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| Other Authors: | , , , |
| Format: | Electronic |
| Language: | English |
| Published: |
Dordrecht :
Springer Netherlands,
2002.
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| Series: | Current Applications of Cell Culture Engineering,
2 |
| Subjects: | |
| Online Access: | View fulltext via EzAccess |
Table of Contents:
- Insect Cell Lines
- Development and characterization of insect cell lines
- New approaches to insect tissue culture
- Transgenic insect cells: mosquito cell mutants and the dihydrofolate reductase gene
- Insect cell physiology
- Insect cell cultivation: growth and kinetics
- Medium design for insect cell culture
- Viruses
- Baculovirus-insect cell interactions
- Replication patterns and cytopathology of cells infected with baculoviruses
- Construction of baculovirus recombinants
- Passage effect of virus infection in insect cells
- Post-translational modifications in insect cells
- Productivity of insect cells for recombinant proteins
- Chaperone and foldase coexpression in the baculovirus-insect cell expression system
- Engineering Aspects
- Shear sensitivity of insect cells
- Insect cell bioreactors
- Perfusion bioreactors for the production of recombinant proteins in insect cells
- Immobilization of insect cells
- Modelling baculovirus infection of insect cells in culture
- Scale up aspects of sparged insect-cell bioreactors
- Oxygen gradients in small and big sparged insect-cell bioreactors
- Downstream processing of insect cell cultures
- Applications
- Parvovirus diagnostics and vaccine production in insect cells
- Classical swine fever virus diagnostics and vaccine production in insect cells
- Production of multidomain complement glycoproteins in insect cells
- Economic and Regulatory Aspects
- Economics of baculovirus-insect cell production systems
- Safety aspects of insect cell culture
- Regulatory issues in the use of insect-cell culture.