Immunotoxicology and Risk Assessment

• Main Author: Flaherty, Dennis K. (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic
• Language: English
• Published: Boston, MA : Springer US, 1999.
• Subjects: Medicine.; Pharmacology.; Environmental management.; Air pollution.; Biomedicine.; Pharmacology/Toxicology.; Environmental Management.; Atmospheric Protection/Air Quality Control/Air Pollution.
• Online Access: View fulltext via EzAccess

This authored book presents basic immunological tenets and mechanisms at the cellular and molecular level while employing the toxicology focus on hazard identification, appropriate assays, dose response, and risk assesment by mathematical models and safety factors. It will be a useful reference to t...

Table of Contents:

• to Immunotoxicology
• Innate Immunity
• Cells of the Immune System
• Immunogenicity and Antigenicity
• Antigen-Presenting Cells
• Antigen Presentation
• Surface Interactions and Intracellular Signaling
• B-Cell Activation
• Antibodies
• Immunological Memory
• Complement
• Phagocytosis and Intracellular Killing
• Immediate Hypersensitivity Reactions
• Autoimmunity
• Delayed Hypersensitivity Reactions
• Killer Cells
• Killer Cells and Viral Infections
• Transplantation
• The Kines
• Assessment of Biological Significance
• Risk Characterization
• References.