Amino acids in human nutrition and health /

• Format: eBook
• Language: English
• Published: Wallingford, Oxfordshire, UK : CABI, 2012.
• Subjects: Amino acids in human nutrition.; Amino aicds > Metabolism.; Amino Acids > metabolism.; Amino Acids > therapeutic use.; Enzymes > metabolism.; Enzymes > therapeutic use.; Nutritional Physiological Phenomena.; Animal Nutrition (Physiology); Human Genetics and Molecular Medicine, (New June 2002); Physiology of Human Nutrition.; Molecular Biology and Molecular Genetics, (Discontinued March 2000, Reinstated and Revised June 2002); Man.; Amino acids.; Biochemical markers.; Biochemistry.; Brain.; Cognitive development.; Enzymes.; Health.; Kinetics.; Metabolism.; Molecular genetics.; Nutrition.; Electronic books.
• Online Access: View fulltext via EzAccess

 The chapters in this book are arranged within a thematic structure as indicated in the sections below. The first part pursues the theme of amino acid metabolism through the driving actions of the principal enzymes, emphasizing recent developments particularly with reference to localization, molecular genetics, biophysical characterization and regulation. Subsequent chapters will also demonstrate the changing facets of amino acid biochemistry. The competing actions of enzymes for critical substrates are also features of relevance in this section. A number of the enzymes under review here catalyse rate-limiting steps in important metabolic pathways, leading to synthesis of physiologically active intermediates and end products. There is scope for elaboration of the important pathways initiated by enzymes under review in this section. Part I has also been developed with the aim of underpinning subsequent chapters in this volume. Part II deals with important issues relating to whole-body amino acid dynamics, with a particular objective of supporting the chapters on nutrition and health that will follow. In this chapter, authors were encouraged to adopt an integrative approach to include their own expertise and that of others in their respective fields. A basic outline of metabolic pathways appears in Part I. The theme in this section centres around kinetics and regulation in broad-spectrum reviews incorporating innovative aspects of the relevant research. In other words, the concept of metabolic networking forms an underlying theme in this series of chapters. The chapters in part III cover a number of topical research investigations employing existing technologies to develop novel concepts or to underpin contemporary practices. At least four of the chapters in part IV focus on different amino acids associated with neurological issues and cognitive performance measures. The approach here is designed to reflect developments in epidemiology, monitoring, and clinical interventions in the various conditions under consideration in this section. The final section contains a plenary review designed to summarize the main findings in the foregoing chapters within an integrated account. The main theme centres around the concept of the emergence of a new momentum driving forward a progressive agenda in further elucidating the biochemical and health implications of amino acids.