Macrocyclic lactones in antiparasitic therapy /

• Format: eBook
• Language: English
• Published: Wallingford, Oxfordshire, UK : CABI, 2002.
• Subjects: Avermectins.; Lactones.; Macrocyclic compounds.; Antiparasitic agents.; Pesticides and Drugs; Control, (New March 2000); Pesticide and Drug Resistance.; Protozoan, Helminth, Mollusc and Arthropod Parasites of Animals, (New March 2000); Veterinary Pharmacology and Anaesthesiology, (New March 2000); Protozoan, Helminth and Arthropod Parasites of Humans, (New March 2000); Cats.; Cattle.; Dogs.; Goats.; Horses.; Man.; Pigs.; Ruminants.; Sheep.; Anthelmintics.; Disease control.; Drug resistance.; Drug therapy.; Introduced species.; Mode of action.; Pets.; Pharmacokinetics.; Pharmacology.; Resistance mechanisms.; Safety.; Electronic books.
• Online Access: View fulltext via EzAccess

This book contains 14 chapters on macrocyclic lactones (MLs). Chapter 1 covers chemistry, pharmacology and drug safety and chapter 2 deals with pharmacokinetics. New information on the mode of action emphasizing glutamate-gated chloride ion channels are reviewed in chapter 3. The impact of MLs on du...

Table of Contents:

• Chemistry, Pharmacology and Safety of the Macrocyclic Lactones
• Ivermectin, Abamectin and Eprinomectin / W. Shoop and M. Soll
• Doramectin and Selamectin / G.A. Conder and W.J. Baker
• Milbemycin Oxime / M. Jung, A. Saito, G. Buescher, M. Maurer and J.-F. Graf
• Moxidectin / D.W. Rock, R.L. DeLay and M.J. Gliddon
• Pharmacokinetics of the Macrocyclic Lactones : Conventional Wisdom and New Paradigms / D.R. Hennessy and M.R. Alvinerie
• Mode of Action of the Macrocyclic Lactones / R.J. Martin, A.P. Robertson and A.J. Wolstenholme
• Ecological Impact of Macrocyclic Lactones on Dung Fauna / J.W. Steel and K.G. Wardhaugh
• Resistance Against Macrocyclic Lactones / R.K. Prichard
• The Use of Macrocyclic Lactones to Control Parasites of Cattle
• General Efficacy of the Macrocyclic Lactones to Control Parasites of Cattle / J. Vercruysse and R. Rew
• Use of Macrocyclic Lactones to Control Cattle Parasites in Europe / J. Vercruysse and R. Rew
• Use of Macrocyclic Lactones to Control Cattle Parasites in the USA and Canada / R. Rew and J. Vercruysse
• Use of Macrocyclic Lactones to Control Cattle Parasites in South America / C. Eddi, A. Nari and J. Caracostantogolo
• Use of Macrocyclic Lactones to Control Cattle Parasites in Australia and New Zealand / P.A. Holdsworth
• The Use of Macrocyclic Lactones to Control Parasites of Sheep and Goats / R.L. Coop, I. Barger and F. Jackson
• The Use of Macrocyclic Lactones to Control Parasites of Horses / C.M. Monahan and T.R. Klei
• The Use of Macrocyclic Lactones to Control Parasites of Pigs / J. Arends and J. Vercruysse
• The Use of Macrocyclic Lactones in the Control and Prevention of Heartworm and Other Parasites in Dogs and Cats / J. Guerrero, J.W. McCall and C. Genchi
• The Use of Macrocyclic Lactones to Control Parasites of Domesticated Wild Ruminants / S.E. Marley and G.A. Conder
• The Use of Macrocyclic Lactones to Control Parasites of Exotic Pets / S.E. Little, C.B. Greenacre and R.M. Kaplan
• The Use of Macrocyclic Lactones to Control Parasites of Humans / K.R. Brown
• Macrocyclic Lactones as Antiparasitic Agents in the Future / T.G. Geary.