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Growth in the pharmaceutical market has slowed down <U+0013> almost to a standstill. One reason is that governments and other payers are cutting costs in a faltering world economy. But a more fundamental problem is the failure of major companies to discover, develop and market new drugs. Major...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Prokop, Alea. (Editor), Csuks̀, Bľa. (Editor)
Format: Electronic
Language:English
Published: Dordrecht : Springer Netherlands : Imprint: Springer, 2013.
Subjects:
Online Access:https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-94-007-6803-1
Table of Contents:
  • Functional genomics, proteomics, metabolomics and bioinformatics for systems biology
  • Comparing biological networks: a survey on graph classifying techniques
  • Emergent properties of gene regulatory networks <U+0013> models and data
  • Regulatory crosstalk analysis of biochemical networks in the nucleus accumbens
  • Properties of biological networks
  • Network analysis for systems biology
  • Computational approaches for reconstruction of time-varying biological networks from Omics data
  • Probabilistic graphical modeling in systems biology: a framework for integrative approaches
  • Innovations of the rule-based modeling approach
  • Reproducibility of model-based results in systems biology
  • Parameter identifiability and redundancy, with applications to a general class of stochastic carcinogenesis models
  • Semantic systems biology: formal knowledge representation in systems biology for model construction, retrieval, validation and discovery
  • Computational infrastructures for data and knowledge management in systems biology
  • Computational tools and resources for integrative modeling in systems biology
  • Agent-based modeling approaches to multi-scale systems biology: An example agent-based model of acute pulmonary inflammation
  • Reconstructing cellular signaling and regulatory networks - an integrative approach for systems-level drug discovery
  • A survey of current integrative network algorithms for systems biology
  • Direct Computer Mapping based modeling of a multiscale process, involving p53/miR-34a signaling.