Structure and Physics of Viruses An Integrated Textbook /

Structural Virology is today an all-important scientific discipline that permeates most other virological disciplines. The application of physical and physicochemical techniques has led to the determination of the high-resolution molecular structures of many viruses. The interplay of this approach w...

Full description

Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Mateu, Mauricio G. (Editor)
Format: Electronic
Language:English
Published: Dordrecht : Springer Netherlands : Imprint: Springer, 2013.
Series:Subcellular Biochemistry, 68
Subjects:
Online Access:https://ezaccess.library.uitm.edu.my/login?url=http://dx.doi.org/10.1007/978-94-007-6552-8
Table of Contents:
  • Introduction: the structural basis of virus function
  • The basic architecture of viruses
  • Conventional electron microscopy, cryo-electron microscopy and cryo-electron tomography of viruses
  • X-ray crystallography of viruses.-�Nuclear magnetic resonance spectroscopy to study virus structure
  • Fluorescence, circular dichroism and mass spectrometry as tools to study virus structure
  • Combined approaches to study virus structure
  • Atomic force microscopy of viruses
  • Optical tweezers to study viruses
  • Assembly of simple icosahedral viruses
  • Structure and assembly of complex viruses
  • Nucleic acid packaging in viruses
  • Virus maturation
  • Virus morphogenesis in the cell: methods and observations
  • Virus-receptor interactions and receptor-mediated virus entry into host cells
  • Entry of enveloped viruses into host cells: membrane fusion
  • Bacteriophage receptor recognition and nucleic acid transfer.-�Mechanical properties of viruses
  • Theoretical studies on assembly, physical stability and dynamics of viruses
  • Antiviral agents: Structural basis of action and rational design
  • Design of novel vaccines based on virus-like particles or chimeric virions
  • Nanoscale science and technology with plant viruses and bacteriophages.